Abstract

Non-motor symptoms (NMS) of Parkinson's disease (PD) are well described in both clinical practice and the literature, enabling their management and enhancing our understanding of PD. NMS can dominate the clinical pictures and NMS subtypes have recently been proposed, initially based on clinical observations, and later confirmed in data driven analyses of large datasets and in biomarker-based studies. In this chapter, we provide an update on what is known about three common subtypes of NMS in PD. The pain (Park-pain), sleep dysfunction (Park-sleep), and autonomic dysfunction (Park-autonomic), providing an overview of their individual classification, clinical manifestation, pathophysiology, diagnosis, and potential treatments.

Original languageEnglish
Title of host publicationInternational Review of Neurobiology
PublisherACADEMIC PRESS INC
DOIs
Publication statusAccepted/In press - 2023

Publication series

NameInternational Review of Neurobiology
ISSN (Print)0074-7742
ISSN (Electronic)2162-5514

Keywords

  • Autonomic dysfunction
  • Cardiovascular
  • Gastrointestinal
  • Non-motor
  • Pain
  • Parkinson's
  • Sleep
  • Urogenital

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