Sex bias in autism: new insights from Chd8 mutant mice?

Laura C. Andreae, M. Albert Basson*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

A study has found that young male mice with a mutation of the autism-associated gene Chd8 show abnormal behaviors and elevated neuronal activation in several brain areas under stressful conditions, while female mice with the same mutation have reduced baseline neuronal activity, which may protect them from developing these abnormal phenotypes.

Original languageEnglish
JournalNature Neuroscience
DOIs
Publication statusAccepted/In press - 1 Jan 2018

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