Sex differences in the clinical presentation, resource use, and 3-month outcome of acute stroke in Europe - Data from a multicenter multinational hospital-based registry

A Di Carlo, M Lamassa, M Baldereschi, G Pracucci, A M Basile, C D A Wolfe, M Giroud, A Rudd, A Ghetti, D Inzitari, European BIOMED Study of Stroke Care

Research output: Contribution to journalArticlepeer-review

546 Citations (Scopus)

Abstract

Background and Purpose - The information on the existence of sex differences in management of stroke patients is scarce. We evaluated whether sex differences may influence clinical presentation, resource use, and outcome of stroke in a European multicenter study. Methods - In a European Concerted Action involving 7 countries, 4499 patients hospitalized for first-in-a-lifetime stroke were evaluated for demographics, risk factors, clinical presentation, resource use, and 3-month survival, disability (Barthel Index), and handicap (Rankin Scale). Results - Overall, 2239 patients were males and 2260 females. Compared with males, female patients were significantly older (mean age 74.5 +/- 12.5 versus 69.2 +/- 12.1 years), more frequently institutionalized before stroke, and with a worse prestroke Rankin score (all values P <0.001). History of hypertension ( P = 0.007) and atrial fibrillation ( P <0.001) were significantly more frequent in female stroke patients, as were coma (P <0.001), paralysis (P
Original languageEnglish
Pages (from-to)1114 - 1119
Number of pages6
JournalStroke
Volume34
Issue number5
DOIs
Publication statusPublished - 1 May 2003

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