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Silent T1 mapping using the variable flip angle method with B1 correction

Research output: Contribution to journalArticle

Emil Ljungberg, Tobias Wood, Ana Beatriz Solana, Shannon Kolind, Steven C R Williams, Florian Wiesinger, Gareth J Barker

Original languageEnglish
Pages (from-to)813-824
Number of pages12
JournalMagnetic Resonance in Medicine
Issue number2
Early online date21 Jan 2020
Publication statusPublished - 1 Aug 2020

Bibliographical note

© 2020 International Society for Magnetic Resonance in Medicine.


  • Ljungberg2020_Silent_T1mapping_PP

    PrePeerReview_PURE.pdf, 2.51 MB, application/pdf


    Submitted manuscript

    CC BY

    This is the pre-peer reviewed version of the following article: Ljungberg, E, Wood, T, Solana, AB, et al. Silent T1 mapping using the variable flip angle method with B1 correction. Magn Reson Med. 2020; 00: 1–12. which has been published in final form at This article may be used for non- commercial purposes in accordance with Wiley Terms and Conditions for Use of Self- Archived Versions.

King's Authors


Purpose: To compare the silent rotating ultrafast imaging sequence (RUFIS) to a traditional Cartesian spoiled gradient-echo (SPGR) acquisition scheme for variable flip angle (VFA) (Formula presented.) mapping. Methods: A two-point VFA measurement was performed using RUFIS and Cartesian SPGR in a quantitative phantom and healthy volunteers. To correct for (Formula presented.) errors, a novel silent magnetization prepared (Formula presented.) map acquisition (SIMBA) was developed, which combined with RUFIS VFA allows for a completely silent (Formula presented.) mapping protocol. Results: The silent protocol was found to have comparable repeatability but higher reproducibility in vivo compared to the standard SPGR protocol, and showed no increase in acoustic noise levels above background noise levels compared to a 33 dBA increase for the SPGR acquisition. Conclusions: VFA (Formula presented.) mapping using RUFIS is a feasible alternative to SPGR, achieving silent (Formula presented.) mapping with comparable acquisition time.

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