SimICD: A Closed-Loop Simulation Framework For ICD Therapy

TY - CHAP

T1 - SimICD: A Closed-Loop Simulation Framework For ICD Therapy

AU - Lydon, Hannah

AU - Kazemi Mehrabadi, Milad

AU - Bishop, Martin

AU - Paoletti, Nicola

PY - 2025/4/8

Y1 - 2025/4/8

N2 - Virtual studies of ICD behaviour are crucial for testing device functionality in a controlled environment prior to clinical application. Although previous works have shown the viability of using in silico testing for diagnosis, there is a notable gap in available models that can simulate therapy progression decisions during arrhythmic episodes. This work introduces SimICD, a simulation tool which combines virtualICD logic algorithms with cardiac electrophysiology simulations in a feedback loop, allowing the progression of ICD therapy protocols to be simulated for a range of tachy-arrhythmia episodes. Using a cohort of virtual patients, we demonstratethe ability of SimICD to simulate realistic cardiac signals and ICD responses that align with the logic of real-world devices, facilitating the reprogramming of ICD parameters to adapt to specific episodes.

AB - Virtual studies of ICD behaviour are crucial for testing device functionality in a controlled environment prior to clinical application. Although previous works have shown the viability of using in silico testing for diagnosis, there is a notable gap in available models that can simulate therapy progression decisions during arrhythmic episodes. This work introduces SimICD, a simulation tool which combines virtualICD logic algorithms with cardiac electrophysiology simulations in a feedback loop, allowing the progression of ICD therapy protocols to be simulated for a range of tachy-arrhythmia episodes. Using a cohort of virtual patients, we demonstratethe ability of SimICD to simulate realistic cardiac signals and ICD responses that align with the logic of real-world devices, facilitating the reprogramming of ICD parameters to adapt to specific episodes.

M3 - Conference paper

BT - 47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

ER -