Simple conjugated polymer nanoparticles as biological labels

TY - JOUR

T1 - Simple conjugated polymer nanoparticles as biological labels

AU - Green, Mark

AU - Howes, Philip

AU - Berry, Catherine

AU - Argyros, Orestis

AU - Thanou, Maya

PY - 2009/9/8

Y1 - 2009/9/8

N2 - The use of nanoparticles in biology, especially in cellular imaging, is extremely promising and offers numerous advantages over existing organic dye systems. There are, however, constraints that need to be addressed before the use of such materials in mainstream clinical applications can be realized. One of the main concerns is the use of metal-containing particles that are potentially toxic or interfere with other diagnostic processes. Here, we present the use of simple conjugated polymer nanoparticles as alternative photostable cellular optical imaging agents.

AB - The use of nanoparticles in biology, especially in cellular imaging, is extremely promising and offers numerous advantages over existing organic dye systems. There are, however, constraints that need to be addressed before the use of such materials in mainstream clinical applications can be realized. One of the main concerns is the use of metal-containing particles that are potentially toxic or interfere with other diagnostic processes. Here, we present the use of simple conjugated polymer nanoparticles as alternative photostable cellular optical imaging agents.

U2 - 10.1098/rspa.2009.0181

DO - 10.1098/rspa.2009.0181

M3 - Article

SN - 1471-2946

VL - 465

SP - 2751

EP - 2759

JO - Royal Society of London. Proceedings A. Mathematical, Physical and Engineering Sciences

JF - Royal Society of London. Proceedings A. Mathematical, Physical and Engineering Sciences

IS - 2109

ER -