TY - JOUR
T1 - Simultaneous high-resolution cardiac T1 mapping and cine imaging using model-based iterative image reconstruction
AU - Becker, Kirsten M.
AU - Schulz-Menger, Jeanette
AU - Schaeffter, Tobias
AU - Kolbitsch, Christoph
PY - 2019/2/1
Y1 - 2019/2/1
N2 - Purpose: To provide high-resolution cardiac T1 mapping of various cardiac phases and cine imaging within a single breath-hold using continuous golden ratio-based radial acquisition and model-based iterative image reconstruction. Methods: Data acquisition was performed continuously using golden ratio-based radial sampling and multiple inversion pulses were applied independent of the heart rate. Native T1 maps of diastole and systole were reconstructed with in-plane resolution of 1.3 × 1.3 mm2 using model-based iterative image reconstruction. Cine images with 30 cardiac phases were reconstructed from the same data using kt-SENSE. The method was evaluated in a commercially available T1 phantom and 10 healthy subjects. In vivo T1 assessment was carried out segment-wise. Results: Evaluation in the phantom demonstrated accurate T1 times (R2 > 0.99) and insensitivity to the heart rate. In vivo T1 values did not differ between systole and diastole, and T1 times assessed by the proposed approach were longer than measured with a modified Look-Locker inversion recovery (MOLLI) sequence, except for lateral segments. Cine images had a consistent dark-blood contrast and functional assessment was in agreement with assessment based on Cartesian cine scans (difference in ejection fraction: 0.26 ± 2.65%, P = 0.65). Conclusion: The proposed approach provides native T1 maps of diastole and systole with high spatial resolution and cine images simultaneously within 16 s, which could strongly improve the scan efficiency.
AB - Purpose: To provide high-resolution cardiac T1 mapping of various cardiac phases and cine imaging within a single breath-hold using continuous golden ratio-based radial acquisition and model-based iterative image reconstruction. Methods: Data acquisition was performed continuously using golden ratio-based radial sampling and multiple inversion pulses were applied independent of the heart rate. Native T1 maps of diastole and systole were reconstructed with in-plane resolution of 1.3 × 1.3 mm2 using model-based iterative image reconstruction. Cine images with 30 cardiac phases were reconstructed from the same data using kt-SENSE. The method was evaluated in a commercially available T1 phantom and 10 healthy subjects. In vivo T1 assessment was carried out segment-wise. Results: Evaluation in the phantom demonstrated accurate T1 times (R2 > 0.99) and insensitivity to the heart rate. In vivo T1 values did not differ between systole and diastole, and T1 times assessed by the proposed approach were longer than measured with a modified Look-Locker inversion recovery (MOLLI) sequence, except for lateral segments. Cine images had a consistent dark-blood contrast and functional assessment was in agreement with assessment based on Cartesian cine scans (difference in ejection fraction: 0.26 ± 2.65%, P = 0.65). Conclusion: The proposed approach provides native T1 maps of diastole and systole with high spatial resolution and cine images simultaneously within 16 s, which could strongly improve the scan efficiency.
KW - cine imaging
KW - model-based reconstruction
KW - multiparametric acquisition
KW - myocardial tissue characterization
KW - T mapping
UR - http://www.scopus.com/inward/record.url?scp=85052926063&partnerID=8YFLogxK
U2 - 10.1002/mrm.27474
DO - 10.1002/mrm.27474
M3 - Article
C2 - 30183094
AN - SCOPUS:85052926063
SN - 0740-3194
VL - 81
SP - 1080
EP - 1091
JO - Magnetic Resonance in Medicine
JF - Magnetic Resonance in Medicine
IS - 2
ER -
