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Simultaneous high-resolution cardiac T1 mapping and cine imaging using model-based iterative image reconstruction

Research output: Contribution to journalArticlepeer-review

Kirsten M. Becker, Jeanette Schulz-Menger, Tobias Schaeffter, Christoph Kolbitsch

Original languageEnglish
Pages (from-to)1080-1091
Number of pages12
JournalMagnetic Resonance in Medicine
Issue number2
Accepted/In press9 Jul 2018
Published1 Feb 2019

King's Authors


Purpose: To provide high-resolution cardiac T1 mapping of various cardiac phases and cine imaging within a single breath-hold using continuous golden ratio-based radial acquisition and model-based iterative image reconstruction. Methods: Data acquisition was performed continuously using golden ratio-based radial sampling and multiple inversion pulses were applied independent of the heart rate. Native T1 maps of diastole and systole were reconstructed with in-plane resolution of 1.3 × 1.3 mm2 using model-based iterative image reconstruction. Cine images with 30 cardiac phases were reconstructed from the same data using kt-SENSE. The method was evaluated in a commercially available T1 phantom and 10 healthy subjects. In vivo T1 assessment was carried out segment-wise. Results: Evaluation in the phantom demonstrated accurate T1 times (R2 > 0.99) and insensitivity to the heart rate. In vivo T1 values did not differ between systole and diastole, and T1 times assessed by the proposed approach were longer than measured with a modified Look-Locker inversion recovery (MOLLI) sequence, except for lateral segments. Cine images had a consistent dark-blood contrast and functional assessment was in agreement with assessment based on Cartesian cine scans (difference in ejection fraction: 0.26 ± 2.65%, P = 0.65). Conclusion: The proposed approach provides native T1 maps of diastole and systole with high spatial resolution and cine images simultaneously within 16 s, which could strongly improve the scan efficiency.

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