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Sleep problems in adolescents with CFS: a case control study nested within a prospective clinical cohort

Research output: Contribution to journalArticle

Original languageEnglish
JournalClinical Child Psychology and Psychiatry
Publication statusAccepted/In press - 20 Mar 2020


  • SLAM Paper 10 Sleep paper v8 r2 COMPLETE

    SLAM_Paper_10_Sleep_paper_v8_r2_COMPLETE.docx, 159 KB, application/vnd.openxmlformats-officedocument.wordprocessingml.document


    Accepted author manuscript


King's Authors


Sleep problems have a negative impact on a range of outcomes and are a very common symptom in adolescents with chronic fatigue syndrome (CFS). We aimed to a) establish whether adolescents with CFS have more self-reported sleep problems than illness controls as well as healthy controls, b) investigate changes in sleep problems and c) explore the extent to which sleep problems at baseline predict fatigue and functioning at follow-up in adolescents with CFS. The Insomnia Scale was completed by 121 adolescents with CFS, 78 healthy adolescents, and 27 adolescents with asthma. Eighty (66%) treatment naïve adolescents with CFS completed questionnaires approximately 3 months later. Adolescents with CFS reported increased sleep problems compared to healthy controls and adolescents with asthma. In CFS, there was no significant change in sleep problems without treatment over a 3-month follow-up. Sleep problems at baseline predicted a significant proportion of the variance in sleep problems at follow-up. Sleep problems should be targeted in treatment. Regulating the “body clock” via the regulation of sleep could influence outcomes not assessed in this study such as school attainment

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