Small molecules in an RNAi world

Ulrike S Eggert; Ulrike Eggert; Christine M Field; Timothy J Mitchison

doi:10.1039/b515335b

Small molecules in an RNAi world

Ulrike S Eggert, Ulrike Eggert, Christine M Field, Timothy J Mitchison

Harvard Medical School

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

In this Opinion, we compare and contrast small molecules and RNAi. We discuss the advantages and disadvantages of both technologies focusing on timing, specificity, dose and therapeutic use.

Original language	English
Pages (from-to)	93-96
Number of pages	4
Journal	Molecular Biosystems
Volume	2
Issue number	2
DOIs	https://doi.org/10.1039/b515335b
Publication status	Published - Feb 2006

Keywords

Animals
Dose-Response Relationship, Drug
Humans
Models, Biological
RNA Interference
RNA, Small Interfering
Sensitivity and Specificity
Time Factors

Access to Document

10.1039/b515335b

Cite this

@article{b49ef72e11104b738056c6dec4ab8294,

title = "Small molecules in an RNAi world",

abstract = "In this Opinion, we compare and contrast small molecules and RNAi. We discuss the advantages and disadvantages of both technologies focusing on timing, specificity, dose and therapeutic use.",

keywords = "Animals, Dose-Response Relationship, Drug, Humans, Models, Biological, RNA Interference, RNA, Small Interfering, Sensitivity and Specificity, Time Factors",

author = "Eggert, {Ulrike S} and Ulrike Eggert and Field, {Christine M} and Mitchison, {Timothy J}",

year = "2006",

month = feb,

doi = "10.1039/b515335b",

language = "English",

volume = "2",

pages = "93--96",

journal = "Molecular Biosystems",

issn = "1742-206X",

publisher = "Royal Society of Chemistry",

number = "2",

}

TY - JOUR

T1 - Small molecules in an RNAi world

AU - Eggert, Ulrike S

AU - Eggert, Ulrike

AU - Field, Christine M

AU - Mitchison, Timothy J

PY - 2006/2

Y1 - 2006/2

N2 - In this Opinion, we compare and contrast small molecules and RNAi. We discuss the advantages and disadvantages of both technologies focusing on timing, specificity, dose and therapeutic use.

AB - In this Opinion, we compare and contrast small molecules and RNAi. We discuss the advantages and disadvantages of both technologies focusing on timing, specificity, dose and therapeutic use.

KW - Animals

KW - Dose-Response Relationship, Drug

KW - Humans

KW - Models, Biological

KW - RNA Interference

KW - RNA, Small Interfering

KW - Sensitivity and Specificity

KW - Time Factors

U2 - 10.1039/b515335b

DO - 10.1039/b515335b

M3 - Article

C2 - 16880926

SN - 1742-206X

VL - 2

SP - 93

EP - 96

JO - Molecular Biosystems

JF - Molecular Biosystems

IS - 2

ER -

Small molecules in an RNAi world

Abstract

Keywords

Access to Document

Fingerprint

Cite this