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Space-time variant weighted regularization in compressed sensing cardiac cine MRI

Research output: Contribution to journalArticlepeer-review

Alejandro Godino-Moya, Javier Royuela-del-Val, Muhammad Usman, Rosa María Menchón-Lara, Marcos Martín-Fernández, Claudia Prieto, Carlos Alberola-López

Original languageEnglish
Pages (from-to)44-55
Number of pages12
JournalMagnetic Resonance Imaging
Early online date14 Jan 2019
Accepted/In press5 Jan 2019
E-pub ahead of print14 Jan 2019
PublishedMay 2019

King's Authors



To analyze the impact on image quality and motion fidelity of a motion-weighted space-time variant regularization term in compressed sensing cardiac cine MRI.


k-t SPARSE-SENSE with temporal total variation (tTV) is used as the base reconstruction algorithm. Motion in the dynamic image is estimated by means of a robust registration technique for non-rigid motion. The resulting deformation fields are used to leverage the regularization term. The results are compared with standard k-t SPARSE-SENSE with tTV regularization as well as with an improved version of this algorithm that makes use of tTV and temporal Fast Fourier Transform regularization in x-f domain.


The proposed method with space-time variant regularization provides higher motion fidelity and image quality than the two previously reported methods. Difference images between undersampled reconstruction and fully sampled reference images show less systematic errors with the proposed approach.


Usage of a space-time variant regularization offers reconstructions with better image quality than the state of the art approaches used for comparison.

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