Spatial variation of blood viscosity: Modelling using shear fields measured by a mu PIV based technique

Efstathios Kaliviotis, Jonathan Dusting, Stavroula Balabani

    Research output: Contribution to journalArticlepeer-review

    20 Citations (Scopus)


    The spatial characteristics of blood viscosity were investigated by combining a newly developed constitutive equation with shear deformation fields calculated from velocity measurements obtained by a mu PIV based technique. Blood at physiological hematocrit levels and in the presence of aggregation was sheared in a narrow gap plate-plate geometry and the velocity and aggregation characteristics were determined from images captured using a high resolution camera. Changes in the microstructure of blood caused by aggregation were observed to affect the flow characteristics. At low shear rates, high aggregation and network formation caused the RBC motion to become essentially two-dimensional. The measured velocity fields were used to estimate the magnitude of shear which was subsequently used in conjunction with the new model to assess the spatial variation of viscosity across the flow domain. It was found that the non-uniform microstructural characteristics of blood influence its viscosity distribution accordingly. The viscosity of blood estimated in the core of the examined flow, using a zero-gradient core velocity profile assumption, was found to be significantly higher than the overall effective viscosity determined using other velocity profile assumptions. (C) 2010 IPEM. Published by Elsevier Ltd. All rights reserved.
    Original languageEnglish
    Pages (from-to)824 - 831
    Number of pages8
    JournalMedical Engineering and Physics
    Issue number7
    Publication statusPublished - Sept 2011


    Dive into the research topics of 'Spatial variation of blood viscosity: Modelling using shear fields measured by a mu PIV based technique'. Together they form a unique fingerprint.

    Cite this