King's College London

Research portal

Speech-related visualization of laryngeal muscles with fluorine-18-FDG

Research output: Contribution to journalArticle

L. Kostakoglu, J. C. H. Wong, S. F. Barrington, B. F. Cronin, A. M. Dynes, M. N. Maisey

Original languageUndefined/Unknown
Pages (from-to)1771-1773
Number of pages3
JournalJournal of Nuclear Medicine
Issue number11
Publication statusPublished - Nov 1996

Bibliographical note

M1 - 11 Times Cited: 43

King's Authors


This study describes the physiological uptake of F-18-fluoro-2-deoxyglucose (FDG) by the laryngeal muscles secondary to activation of the patient's vocal folds and related laryngeal muscles during speech. Methods: Twenty-four patients undergoing routine PET scans were randomized into two groups to ascertain the relationship between FDG uptake in the laryngeal region and speech. One group was assigned to talk and the other group remained silent during the injection and uptake period of FDG. Results: FDG uptake in the laryngeal muscles in the scans was correlated with speech. Patients who spoke continually during the uptake period had high-grade FDG uptake, those who spoke intermittently had low-grade uptake and those who remained silent had no detectable increase in FDG uptake in the region of the larynx. Conclusion: The relationship between the degree of laryngeal muscle uptake and speech provides useful information to allow differentiation of physiological from pathological uptake in the neck.

View graph of relations

© 2018 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454