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State-of-the-art imaging in oesophago-gastric cancer

Research output: Contribution to journalReview articlepeer-review

Samuel J Withey, Vicky Goh, Kieran G Foley

Original languageEnglish
Article number20220410
Pages (from-to)20220410
JournalBritish Journal of Radiology
Issue number1137
Early online date7 Jun 2022
E-pub ahead of print7 Jun 2022
Published1 Sep 2022

Bibliographical note

Funding Information: SJW was supported by a Cancer Research UK Research Bursary (C66940/A28141). VG acknowledges funding support from Cancer Research UK OCCAMS (Oesophageal Cancer Clinical and Molecular Stratification Consortium) programme grant (RG66287); Cancer Research UK National Imaging Translational Accelerator Award (C4278/A27066); Wellcome EPSRC Centre for Medical Engineering at King’s College London (WT 203148/Z/16/Z); the UKRI Medical Imaging and Artificial Intelligence Centre for Value Based Healthcare; and Department of Health via the NIHR Comprehensive Biomedical Research Centre award to Guy’s & St Thomas' NHS Foundation Trust in partnership with King’s College London/King’s College Hospital NHS Foundation Trust. KGF is supported by research funding from Health and Care Research Wales (HCRW) and the Moon-dance Foundation at Velindre Cancer Centre. Publisher Copyright: © 2022 The Authors.

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Radiological investigations are essential in the management of oesophageal and gastro-oesophageal junction cancers. The current multimodal combination of CT, 18F-fluorodeoxyglucose positron emission tomography combined with CT (PET/CT) and endoscopic ultrasound (EUS) has limitations, which hinders the prognostic and predictive information that can be used to guide optimum treatment decisions. Therefore, the development of improved imaging techniques is vital to improve patient management. This review describes the current evidence for state-of-the-art imaging techniques in oesophago-gastric cancer including high resolution MRI, diffusion-weighted MRI, dynamic contrast-enhanced MRI, whole-body MRI, perfusion CT, novel PET tracers, and integrated PET/MRI. These novel imaging techniques may help clinicians improve the diagnosis, staging, treatment planning, and response assessment of oesophago-gastric cancer.

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