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Stress and cortisol in Parkinson's disease

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish
Title of host publicationInternational Review of Neurobiology
EditorsAngela Clow, Nina Smyth
Number of pages26
ISBN (Print)9780128211168
Accepted/In press1 Jan 2020

Publication series

NameInternational Review of Neurobiology
ISSN (Print)0074-7742
ISSN (Electronic)2162-5514

King's Authors


Stress is ubiquitous with many factors contributing to its effects, including psychological responses and associated biological factors, including cortisol related physiological responses, and inflammation. Also in Parkinson's disease there is growing evidence for the role of stress in some key symptoms, even stretching to the prodromal stage. Here we discuss the possible contributions of the range and nature of stress in PD and we aim to summarize the current knowledge about the role of stress-related responses on motor and non-motor symptoms, the underlying pathophysiology, and the potential implications for treatment.

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