Structural magnetic resonance imaging in eating disorders: a systematic review of voxel-based morphometry studies

Frederique Van den Eynde; Masashi Suda; Hannah Broadbent; Sébastien Guillaume; Magali Van den Eynde; Howard Steiger; Mimi Israel; Marcelo Berlim; Vincent Giampietro; Andrew Simmons; Janet Treasure; Iain Campbell; Ulrike Schmidt

doi:10.1002/erv.1163

Structural magnetic resonance imaging in eating disorders: a systematic review of voxel-based morphometry studies

Frederique Van den Eynde, Masashi Suda, Hannah Broadbent, Sébastien Guillaume, Magali Van den Eynde, Howard Steiger, Mimi Israel, Marcelo Berlim, Vincent Giampietro, Andrew Simmons, Janet Treasure, Iain Campbell, Ulrike Schmidt

Research output: Contribution to journal › Review article › peer-review

113 Citations (Scopus)

Abstract

This systematic review summarises and critically appraises the literature on structural magnetic resonance imaging in people with a current or past eating disorder. Studies using voxel-based morphometry image analysis were included. Ten studies reported on a total of 236 people with a current or past eating disorder and 257 healthy controls. Sample heterogeneity prohibited a meta-analytic approach. The findings do not unequivocally indicate grey or white matter volume abnormalities in people with an eating disorder. Nevertheless, these preliminary data suggest that, compared with healthy controls, people with anorexia nervosa have decreased grey matter in a range of brain regions and that those with bulimia nervosa have increased grey matter volumes in frontal and ventral striatal areas. Research in the recovery phase and longitudinal studies suggest that potential brain tissue abnormalities may recover with clinical improvement. Overall, as the available data are inconclusive, further efforts in this field are warranted.

Original language	English
Pages (from-to)	94-105
Number of pages	12
Journal	European Eating Disorders Review
Volume	20
Issue number	2
Early online date	3 Nov 2011
DOIs	https://doi.org/10.1002/erv.1163
Publication status	Published - Mar 2012

Keywords

Magnetic Resonance Imaging
Bulimia Nervosa
Brain Mapping
Humans
Brain
Anorexia Nervosa
Longitudinal Studies
Image Processing, Computer-Assisted
Eating Disorders

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/erv.1163

Cite this

Van den Eynde, F., Suda, M., Broadbent, H., Guillaume, S., Van den Eynde, M., Steiger, H., Israel, M., Berlim, M., Giampietro, V., Simmons, A., Treasure, J., Campbell, I., & Schmidt, U. (2012). Structural magnetic resonance imaging in eating disorders: a systematic review of voxel-based morphometry studies. European Eating Disorders Review, 20(2), 94-105. https://doi.org/10.1002/erv.1163

@article{07285f15419c4fa2a6cd64701c5a30d4,

title = "Structural magnetic resonance imaging in eating disorders: a systematic review of voxel-based morphometry studies",

abstract = "This systematic review summarises and critically appraises the literature on structural magnetic resonance imaging in people with a current or past eating disorder. Studies using voxel-based morphometry image analysis were included. Ten studies reported on a total of 236 people with a current or past eating disorder and 257 healthy controls. Sample heterogeneity prohibited a meta-analytic approach. The findings do not unequivocally indicate grey or white matter volume abnormalities in people with an eating disorder. Nevertheless, these preliminary data suggest that, compared with healthy controls, people with anorexia nervosa have decreased grey matter in a range of brain regions and that those with bulimia nervosa have increased grey matter volumes in frontal and ventral striatal areas. Research in the recovery phase and longitudinal studies suggest that potential brain tissue abnormalities may recover with clinical improvement. Overall, as the available data are inconclusive, further efforts in this field are warranted.",

keywords = "Magnetic Resonance Imaging, Bulimia Nervosa, Brain Mapping, Humans, Brain, Anorexia Nervosa, Longitudinal Studies, Image Processing, Computer-Assisted, Eating Disorders",

author = "{Van den Eynde}, Frederique and Masashi Suda and Hannah Broadbent and S{\'e}bastien Guillaume and {Van den Eynde}, Magali and Howard Steiger and Mimi Israel and Marcelo Berlim and Vincent Giampietro and Andrew Simmons and Janet Treasure and Iain Campbell and Ulrike Schmidt",

note = "Copyright {\textcopyright} 2011 John Wiley & Sons, Ltd and Eating Disorders Association.",

year = "2012",

month = mar,

doi = "10.1002/erv.1163",

language = "English",

volume = "20",

pages = "94--105",

journal = "European Eating Disorders Review",

issn = "1072-4133",

number = "2",

}

Van den Eynde, F, Suda, M, Broadbent, H, Guillaume, S, Van den Eynde, M, Steiger, H, Israel, M, Berlim, M, Giampietro, V , Simmons, A , Treasure, J , Campbell, I & Schmidt, U 2012, 'Structural magnetic resonance imaging in eating disorders: a systematic review of voxel-based morphometry studies', European Eating Disorders Review, vol. 20, no. 2, pp. 94-105. https://doi.org/10.1002/erv.1163

TY - JOUR

T1 - Structural magnetic resonance imaging in eating disorders

T2 - a systematic review of voxel-based morphometry studies

AU - Van den Eynde, Frederique

AU - Suda, Masashi

AU - Broadbent, Hannah

AU - Guillaume, Sébastien

AU - Van den Eynde, Magali

AU - Steiger, Howard

AU - Israel, Mimi

AU - Berlim, Marcelo

AU - Giampietro, Vincent

AU - Simmons, Andrew

AU - Treasure, Janet

AU - Campbell, Iain

AU - Schmidt, Ulrike

PY - 2012/3

Y1 - 2012/3

N2 - This systematic review summarises and critically appraises the literature on structural magnetic resonance imaging in people with a current or past eating disorder. Studies using voxel-based morphometry image analysis were included. Ten studies reported on a total of 236 people with a current or past eating disorder and 257 healthy controls. Sample heterogeneity prohibited a meta-analytic approach. The findings do not unequivocally indicate grey or white matter volume abnormalities in people with an eating disorder. Nevertheless, these preliminary data suggest that, compared with healthy controls, people with anorexia nervosa have decreased grey matter in a range of brain regions and that those with bulimia nervosa have increased grey matter volumes in frontal and ventral striatal areas. Research in the recovery phase and longitudinal studies suggest that potential brain tissue abnormalities may recover with clinical improvement. Overall, as the available data are inconclusive, further efforts in this field are warranted.

AB - This systematic review summarises and critically appraises the literature on structural magnetic resonance imaging in people with a current or past eating disorder. Studies using voxel-based morphometry image analysis were included. Ten studies reported on a total of 236 people with a current or past eating disorder and 257 healthy controls. Sample heterogeneity prohibited a meta-analytic approach. The findings do not unequivocally indicate grey or white matter volume abnormalities in people with an eating disorder. Nevertheless, these preliminary data suggest that, compared with healthy controls, people with anorexia nervosa have decreased grey matter in a range of brain regions and that those with bulimia nervosa have increased grey matter volumes in frontal and ventral striatal areas. Research in the recovery phase and longitudinal studies suggest that potential brain tissue abnormalities may recover with clinical improvement. Overall, as the available data are inconclusive, further efforts in this field are warranted.

KW - Magnetic Resonance Imaging

KW - Bulimia Nervosa

KW - Brain Mapping

KW - Humans

KW - Brain

KW - Anorexia Nervosa

KW - Longitudinal Studies

KW - Image Processing, Computer-Assisted

KW - Eating Disorders

U2 - 10.1002/erv.1163

DO - 10.1002/erv.1163

M3 - Review article

C2 - 22052722

SN - 1072-4133

VL - 20

SP - 94

EP - 105

JO - European Eating Disorders Review

JF - European Eating Disorders Review

IS - 2

ER -

Structural magnetic resonance imaging in eating disorders: a systematic review of voxel-based morphometry studies

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this