Study of the use of antidepressants for depression in dementia: the HTA-SADD trial - a multicentre, randomised, double-blind, placebo-controlled trial of the clinical effectiveness and cost-effectiveness of sertraline and mirtazapine

S Banerjee, J Hellier, R Romeo, M Dewey, M Knapp, C Ballard, R Baldwin, P Bentham, C Fox, C Holmes, C Katona, C Lawton, J Lindesay, G Livingston, Niall McCrae, E Moniz-Cook, J Murray, S Nurock, M Orrell, J O'BrienM Poppe, A Thomas, R Walwyn, K Wilson, A Burns

Research output: Contribution to journalArticlepeer-review

87 Citations (Scopus)

Abstract

Depression is common in dementia, causing considerable distress and other negative impacts. Treating it is a clinical priority, but the evidence base is sparse and equivocal. This trial aimed to determine clinical effectiveness of sertraline and mirtazapine in reducing depression 13 weeks post randomisation compared with placebo.
Original languageEnglish
Pages (from-to)1-166
Number of pages166
JournalHealth technology assessment (Winchester, England)
Volume17
Issue number7
DOIs
Publication statusPublished - Feb 2013

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