Substantial decline in hospital admissions for heart failure accompanied by increased community mortality during COVID-19 pandemic

Ahmad Shoaib*, Harriette G.C. Van Spall, Jianhua Wu, John G.F. Cleland, Theresa A. Mcdonagh, Muhammad Rashid, Mohamed O. Mohamed, Fozia Z. Ahmed, John Deanfield, Mark De Belder, Chris P. Gale, Mamas A. Mamas

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    44 Citations (Scopus)

    Abstract

    Aims: We hypothesized that a decline in admissions with heart failure during COVID-19 pandemic would lead to a reciprocal rise in mortality for patients with heart failure in the community. Methods and results: We used National Heart Failure Audit data to identify 36 974 adults who had a hospital admission with a primary diagnosis of heart failure between February and May in either 2018, 2019, or 2020. Hospital admissions for heart failure in 2018/19 averaged 160/day but were much lower in 2020, reaching a nadir of 64/day on 27 March 2020 [incidence rate ratio (IRR): 0.40, 95% confidence interval (CI): 0.38-0.42]. The proportion discharged on guideline-recommended pharmacotherapies was similar in 2018/19 compared to the same period in 2020. Between 1 February-2020 and 31 May 2020, there was a 29% decrease in hospital deaths related to heart failure (IRR: 0.71, 95% CI: 0.67-0.75; estimated decline of 448 deaths), a 31% increase in heart failure deaths at home (IRR: 1.31, 95% CI: 1.24-1.39; estimated excess 539), and a 28% increase in heart failure deaths in care homes and hospices (IRR: 1.28, 95% CI: 1.18-1.40; estimated excess 189). All-cause, inpatient death was similar in the COVID-19 and pre-COVID-19 periods [odds ratio (OR): 1.02, 95% CI: 0.94-1.10]. After hospital discharge, 30-day mortality was higher in 2020 compared to 2018/19 (OR: 1.57, 95% CI: 1.38-1.78). Conclusion: Compared with the rolling daily average in 2018/19, there was a substantial decline in admissions for heart failure but an increase in deaths from heart failure in the community. Despite similar rates of prescription of guideline-recommended therapy, mortality 30 days from discharge was higher during the COVID-19 pandemic period.

    Original languageEnglish
    Pages (from-to)378-387
    Number of pages10
    JournalEuropean Heart Journal - Quality of Care and Clinical Outcomes
    Volume7
    Issue number4
    DOIs
    Publication statusPublished - 1 Oct 2021

    Keywords

    • Acute heart failure
    • COVID-19
    • Heart failure
    • Hospitalization
    • Mortality

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