Supportive intervention for fatigue in patients undergoing chemotherapy: A randomized controlled trial

E Ream, A Richardson, C exander-Dann

Research output: Contribution to journalArticlepeer-review

78 Citations (Scopus)

Abstract

This study evaluated a supportive intervention for fatigue in patients undergoing chemotherapy. One hundred three chemotherapy-naive patients were recruited, stratified by treatment regimen, and randomly allocated to intervention or usual care. The intervention was conducted over three months. Recipients were provided with an investigator-designed information pack and Fatigue Diary that they completed during the week following each treatment. Additionally, support nurses visited them monthly at home. They assessed fatigue, provided psychological support, and coached participants in self-care. The intervention group reported significantly less fatigue (P <0.05), lower associated distress (P <0.05), and less impact of fatigue on valued pastimes (P <0.05) than the control group. Further, they reported significantly less anxiety (P <0.05) and depression (P <0.05) and displayed more adaptive coping (P <0.05). The intervention enabled patients to adapt to living with fatigue and contributed to their psychological/emotional well-being and ability to cope with their illness and treatment. J Pain Symptom Manage 2006;31:148-161. (c) 2006 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved
Original languageEnglish
Pages (from-to)148 - 161
Number of pages14
JournalJournal of Pain and Symptom Management
Volume31
Issue number2
DOIs
Publication statusPublished - Feb 2006

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