Surface phosphorylation of chitosan significantly improves osteoblast cell viability, attachment and proliferation

Paula M. López-Pérez, Ricardo M. P. da Silva, Carmen Serra, Iva Pashkuleva, Rui L. Reis

Research output: Contribution to journalArticlepeer-review

61 Citations (Scopus)

Abstract

Chitosan biocompatibility is often associated with the structural similarities with glycosaminoglycans (GAGs). Although all of the GAGs are built from repeating disaccharide units and some of them contain N-glucosamine (the main hexosamine in the chitosan backbone), all of them also contain negatively charge
Original languageEnglish
Pages (from-to)483-491
Number of pages9
JournalJOURNAL OF MATERIALS CHEMISTRY
Volume20
Issue number3
Early online date19 Nov 2009
DOIs
Publication statusPublished - 2010

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