Surface phosphorylation of chitosan significantly improves osteoblast cell viability, attachment and proliferation

Paula M. López-Pérez; Ricardo M. P. da Silva; Carmen Serra; Iva Pashkuleva; Rui L. Reis

doi:10.1039/B911854C

Surface phosphorylation of chitosan significantly improves osteoblast cell viability, attachment and proliferation

Paula M. López-Pérez, Ricardo M. P. da Silva, Carmen Serra, Iva Pashkuleva, Rui L. Reis

Centre for Craniofacial & Regenerative Biology

Research output: Contribution to journal › Article › peer-review

62 Citations (Scopus)

Abstract

Chitosan biocompatibility is often associated with the structural similarities with glycosaminoglycans (GAGs). Although all of the GAGs are built from repeating disaccharide units and some of them contain N-glucosamine (the main hexosamine in the chitosan backbone), all of them also contain negatively charge

Original language	English
Pages (from-to)	483-491
Number of pages	9
Journal	JOURNAL OF MATERIALS CHEMISTRY
Volume	20
Issue number	3
Early online date	19 Nov 2009
DOIs	https://doi.org/10.1039/B911854C
Publication status	Published - 2010

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10.1039/B911854C

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title = "Surface phosphorylation of chitosan significantly improves osteoblast cell viability, attachment and proliferation",

abstract = "Chitosan biocompatibility is often associated with the structural similarities with glycosaminoglycans (GAGs). Although all of the GAGs are built from repeating disaccharide units and some of them contain N-glucosamine (the main hexosamine in the chitosan backbone), all of them also contain negatively charge",

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AU - López-Pérez, Paula M.

AU - Silva, Ricardo M. P. da

AU - Serra, Carmen

AU - Pashkuleva, Iva

AU - Reis, Rui L.

PY - 2010

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N2 - Chitosan biocompatibility is often associated with the structural similarities with glycosaminoglycans (GAGs). Although all of the GAGs are built from repeating disaccharide units and some of them contain N-glucosamine (the main hexosamine in the chitosan backbone), all of them also contain negatively charge

AB - Chitosan biocompatibility is often associated with the structural similarities with glycosaminoglycans (GAGs). Although all of the GAGs are built from repeating disaccharide units and some of them contain N-glucosamine (the main hexosamine in the chitosan backbone), all of them also contain negatively charge

U2 - 10.1039/B911854C

DO - 10.1039/B911854C

M3 - Article

SN - 1364-5501

VL - 20

SP - 483

EP - 491

JO - JOURNAL OF MATERIALS CHEMISTRY

JF - JOURNAL OF MATERIALS CHEMISTRY

IS - 3

ER -

Surface phosphorylation of chitosan significantly improves osteoblast cell viability, attachment and proliferation

Abstract

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