Synchronous ductal carcinoma in situ of the breast and within epithelial inclusions in an ipsilateral sentinel Lymph node

Virginia L. Fitzpatrick-Swallow; Heidi Helin; Paul Cane; Sarah E. Pinder

doi:10.1016/j.humpath.2012.07.012

Synchronous ductal carcinoma in situ of the breast and within epithelial inclusions in an ipsilateral sentinel Lymph node

Virginia L. Fitzpatrick-Swallow^*, Heidi Helin, Paul Cane, Sarah E. Pinder

^*Corresponding author for this work

Comprehensive Cancer Centre

St Thomas Hosp NHS Trust

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Epithelial inclusions in the axillary lymph nodes are very rare and have even less commonly been reported with either benign or malignant changes. We present a case of synchronous high-grade micropapillary ductal carcinoma in situ arising in the breast and in an epithelial inclusion in an ipsilateral sentinel lymph node. Despite extensive sampling, no focus of invasive carcinoma was identified. This unique case highlights the difficulty in diagnosis of metastatic disease when there is a malignant change in an epithelial inclusion in a sentinel lymph node and highlights the need for very careful histologic assessment of such lesions.

Original language	English
Pages (from-to)	142-144
Number of pages	3
Journal	Human Pathology
Volume	44
Issue number	1
DOIs	https://doi.org/10.1016/j.humpath.2012.07.012
Publication status	Published - Jan 2013

Keywords

OF-THE-LITERATURE
TISSUE
Epithelial inclusion
Sentinel node
BENIGN GLANDULAR INCLUSIONS
Ductal carcinoma in situ

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.humpath.2012.07.012

Cite this

@article{6d898cc141d64f358a0f45a114e97eda,

title = "Synchronous ductal carcinoma in situ of the breast and within epithelial inclusions in an ipsilateral sentinel Lymph node",

abstract = "Epithelial inclusions in the axillary lymph nodes are very rare and have even less commonly been reported with either benign or malignant changes. We present a case of synchronous high-grade micropapillary ductal carcinoma in situ arising in the breast and in an epithelial inclusion in an ipsilateral sentinel lymph node. Despite extensive sampling, no focus of invasive carcinoma was identified. This unique case highlights the difficulty in diagnosis of metastatic disease when there is a malignant change in an epithelial inclusion in a sentinel lymph node and highlights the need for very careful histologic assessment of such lesions.",

keywords = "OF-THE-LITERATURE, TISSUE, Epithelial inclusion, Sentinel node, BENIGN GLANDULAR INCLUSIONS, Ductal carcinoma in situ",

author = "Fitzpatrick-Swallow, {Virginia L.} and Heidi Helin and Paul Cane and Pinder, {Sarah E.}",

year = "2013",

month = jan,

doi = "10.1016/j.humpath.2012.07.012",

language = "English",

volume = "44",

pages = "142--144",

journal = "Human Pathology",

issn = "0046-8177",

publisher = "W.B. Saunders Ltd",

number = "1",

}

TY - JOUR

T1 - Synchronous ductal carcinoma in situ of the breast and within epithelial inclusions in an ipsilateral sentinel Lymph node

AU - Fitzpatrick-Swallow, Virginia L.

AU - Helin, Heidi

AU - Cane, Paul

AU - Pinder, Sarah E.

PY - 2013/1

Y1 - 2013/1

N2 - Epithelial inclusions in the axillary lymph nodes are very rare and have even less commonly been reported with either benign or malignant changes. We present a case of synchronous high-grade micropapillary ductal carcinoma in situ arising in the breast and in an epithelial inclusion in an ipsilateral sentinel lymph node. Despite extensive sampling, no focus of invasive carcinoma was identified. This unique case highlights the difficulty in diagnosis of metastatic disease when there is a malignant change in an epithelial inclusion in a sentinel lymph node and highlights the need for very careful histologic assessment of such lesions.

AB - Epithelial inclusions in the axillary lymph nodes are very rare and have even less commonly been reported with either benign or malignant changes. We present a case of synchronous high-grade micropapillary ductal carcinoma in situ arising in the breast and in an epithelial inclusion in an ipsilateral sentinel lymph node. Despite extensive sampling, no focus of invasive carcinoma was identified. This unique case highlights the difficulty in diagnosis of metastatic disease when there is a malignant change in an epithelial inclusion in a sentinel lymph node and highlights the need for very careful histologic assessment of such lesions.

KW - OF-THE-LITERATURE

KW - TISSUE

KW - Epithelial inclusion

KW - Sentinel node

KW - BENIGN GLANDULAR INCLUSIONS

KW - Ductal carcinoma in situ

U2 - 10.1016/j.humpath.2012.07.012

DO - 10.1016/j.humpath.2012.07.012

M3 - Article

SN - 0046-8177

VL - 44

SP - 142

EP - 144

JO - Human Pathology

JF - Human Pathology

IS - 1

ER -

Synchronous ductal carcinoma in situ of the breast and within epithelial inclusions in an ipsilateral sentinel Lymph node

Abstract

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this