Synthesis and CD spectroscopy of polyethers with homochiral and heterochiral layers of stereocentres

TY - JOUR

T1 - Synthesis and CD spectroscopy of polyethers with homochiral and heterochiral layers of stereocentres

AU - Brewer, A R E

AU - Drake, A F

AU - Gibson, S E

AU - Rendell, J T

PY - 2008/7/7

Y1 - 2008/7/7

N2 - Eight polyethers with three to nine stereocentres have been synthesised using chiral base methodology. Examination of the polyethers by CD spectroscopy revealed clear differences between homochiral isomers and isorners with a heterochiral relationship between an 'inner' layer of stereocentres and an outer' layer of stereocentres. A hypothesis to account for these differences has been advanced. (C) 2008 Elsevier Ltd. All rights reserved

AB - Eight polyethers with three to nine stereocentres have been synthesised using chiral base methodology. Examination of the polyethers by CD spectroscopy revealed clear differences between homochiral isomers and isorners with a heterochiral relationship between an 'inner' layer of stereocentres and an outer' layer of stereocentres. A hypothesis to account for these differences has been advanced. (C) 2008 Elsevier Ltd. All rights reserved

U2 - 10.1016/j.tet.2008.05.028

DO - 10.1016/j.tet.2008.05.028

M3 - Article

VL - 64

SP - 6615

EP - 6627

JO - TETRAHEDRON

JF - TETRAHEDRON

IS - 28

ER -