Synthesis and cytotoxicity of 4-(2-Adamantyl)phenylalkylamines

Ioannis Papanastasiou; Stefanos Riganas; George B. Foscolos; Andrew Tsotinis; Samar A. Akhtar; Mohsin A. Khan; Khondaker M. Rahman; David E. Thurston

doi:10.2174/157017861205150509202419

Synthesis and cytotoxicity of 4-(2-Adamantyl)phenylalkylamines

Ioannis Papanastasiou^*, Stefanos Riganas, George B. Foscolos, Andrew Tsotinis, Samar A. Akhtar, Mohsin A. Khan, Khondaker M. Rahman, David E. Thurston

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The design and synthesis of 4-(2-adamantyl)phenylalkylamines 1-4 are described and their antiproliferative activity against four different tumor cell lines is reported.

Original language	English
Pages (from-to)	319-323
Number of pages	5
Journal	LETTERS IN ORGANIC CHEMISTRY
Volume	12
Issue number	5
DOIs	https://doi.org/10.2174/157017861205150509202419
Publication status	Published - 2015

Keywords

4-(2-adamantyl)phenylalkylamines
Antiproliferative activity
C-2 substituted adamantane

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10.2174/157017861205150509202419

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title = "Synthesis and cytotoxicity of 4-(2-Adamantyl)phenylalkylamines",

abstract = "The design and synthesis of 4-(2-adamantyl)phenylalkylamines 1-4 are described and their antiproliferative activity against four different tumor cell lines is reported.",

keywords = "4-(2-adamantyl)phenylalkylamines, Antiproliferative activity, C-2 substituted adamantane",

author = "Ioannis Papanastasiou and Stefanos Riganas and Foscolos, {George B.} and Andrew Tsotinis and Akhtar, {Samar A.} and Khan, {Mohsin A.} and Rahman, {Khondaker M.} and Thurston, {David E.}",

year = "2015",

doi = "10.2174/157017861205150509202419",

language = "English",

volume = "12",

pages = "319--323",

journal = "LETTERS IN ORGANIC CHEMISTRY",

issn = "1570-1786",

publisher = "Bentham Science Publishers B.V.",

number = "5",

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TY - JOUR

T1 - Synthesis and cytotoxicity of 4-(2-Adamantyl)phenylalkylamines

AU - Papanastasiou, Ioannis

AU - Riganas, Stefanos

AU - Foscolos, George B.

AU - Tsotinis, Andrew

AU - Akhtar, Samar A.

AU - Khan, Mohsin A.

AU - Rahman, Khondaker M.

AU - Thurston, David E.

PY - 2015

Y1 - 2015

N2 - The design and synthesis of 4-(2-adamantyl)phenylalkylamines 1-4 are described and their antiproliferative activity against four different tumor cell lines is reported.

AB - The design and synthesis of 4-(2-adamantyl)phenylalkylamines 1-4 are described and their antiproliferative activity against four different tumor cell lines is reported.

KW - 4-(2-adamantyl)phenylalkylamines

KW - Antiproliferative activity

KW - C-2 substituted adamantane

UR - http://www.scopus.com/inward/record.url?scp=84931269941&partnerID=8YFLogxK

U2 - 10.2174/157017861205150509202419

DO - 10.2174/157017861205150509202419

M3 - Article

AN - SCOPUS:84931269941

SN - 1570-1786

VL - 12

SP - 319

EP - 323

JO - LETTERS IN ORGANIC CHEMISTRY

JF - LETTERS IN ORGANIC CHEMISTRY

IS - 5

ER -

Synthesis and cytotoxicity of 4-(2-Adamantyl)phenylalkylamines

Abstract

Keywords

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