T-cell phenotyping uncovers systemic features of atopic dermatitis and psoriasis

Consol Farrera; Rossella Melchiotti; Nedyalko Petrov; Karen  Wei Weng Teng; Michael Thomas Wong; Chiew Yee  Loh; Federica Villanova; Isabella Tosi; Jinmiao Chen; Katarzyna Grys; Hemawtee Sreeneebus; Anna Chapman; Gayathri K. Perera; Susanne Heck; Filipe Gracio; Emanuele de Rinaldis; Jonathan N. Barker; Catherine H. Smith; Frank O. Nestle; Evan W. Newell; Paola Di Meglio

doi:10.1016/j.jaci.2019.11.030

T-cell phenotyping uncovers systemic features of atopic dermatitis and psoriasis

Consol Farrera, Rossella Melchiotti, Nedyalko Petrov, Karen Wei Weng Teng, Michael Thomas Wong, Chiew Yee Loh, Federica Villanova, Isabella Tosi, Jinmiao Chen, Katarzyna Grys, Hemawtee Sreeneebus, Anna Chapman, Gayathri K. Perera, Susanne Heck, Filipe Gracio, Emanuele de Rinaldis, Jonathan N. Barker, Catherine H. Smith, Frank O. Nestle, Evan W. NewellPaola Di Meglio

Dermatology

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Abstract

Deep-immunophenotyping of the circulatory T cell compartment using mass cytometry and unsupervised clustering analysis, identifies phenotypic and functional differences in patients with atopic dermatitis (AD) and psoriasis, highlighting the stronger systemic component associated with AD.

Original language	English
Pages (from-to)	1021-1025.e15
Journal	Journal of Allergy and Clinical Immunology
Volume	145
Issue number	3
Early online date	5 Dec 2019
DOIs	https://doi.org/10.1016/j.jaci.2019.11.030
Publication status	Published - 1 Mar 2020

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10.1016/j.jaci.2019.11.030

T-cell phenotyping uncovers systemic_FARRERA_Accepted27November2019Publishedonline5December2019_GREEN AAM (CC BY-NC-ND)Accepted author manuscript, 2.7 MBLicence: CC BY-NC-ND

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Farrera, C., Melchiotti, R., Petrov, N., Wei Weng Teng, K., Wong, M. T., Loh, C. Y., Villanova, F., Tosi, I., Chen, J., Grys, K., Sreeneebus, H., Chapman, A., Perera, G. K., Heck, S., Gracio, F., de Rinaldis, E., Barker, J. N., Smith, C. H., Nestle, F. O., ... Di Meglio, P. (2020). T-cell phenotyping uncovers systemic features of atopic dermatitis and psoriasis. Journal of Allergy and Clinical Immunology, 145(3), 1021-1025.e15. https://doi.org/10.1016/j.jaci.2019.11.030

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title = "T-cell phenotyping uncovers systemic features of atopic dermatitis and psoriasis",

abstract = "Deep-immunophenotyping of the circulatory T cell compartment using mass cytometry and unsupervised clustering analysis, identifies phenotypic and functional differences in patients with atopic dermatitis (AD) and psoriasis, highlighting the stronger systemic component associated with AD.",

author = "Consol Farrera and Rossella Melchiotti and Nedyalko Petrov and {Wei Weng Teng}, Karen and Wong, {Michael Thomas} and Loh, {Chiew Yee} and Federica Villanova and Isabella Tosi and Jinmiao Chen and Katarzyna Grys and Hemawtee Sreeneebus and Anna Chapman and Perera, {Gayathri K.} and Susanne Heck and Filipe Gracio and {de Rinaldis}, Emanuele and Barker, {Jonathan N.} and Smith, {Catherine H.} and Nestle, {Frank O.} and Newell, {Evan W.} and {Di Meglio}, Paola",

note = "Copyright {\textcopyright} 2019. Published by Elsevier Inc.",

year = "2020",

month = mar,

day = "1",

doi = "10.1016/j.jaci.2019.11.030",

language = "English",

volume = "145",

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Farrera, C, Melchiotti, R, Petrov, N, Wei Weng Teng, K, Wong, MT, Loh, CY, Villanova, F, Tosi, I, Chen, J, Grys, K, Sreeneebus, H, Chapman, A, Perera, GK, Heck, S, Gracio, F, de Rinaldis, E, Barker, JN , Smith, CH , Nestle, FO, Newell, EW & Di Meglio, P 2020, 'T-cell phenotyping uncovers systemic features of atopic dermatitis and psoriasis', Journal of Allergy and Clinical Immunology, vol. 145, no. 3, pp. 1021-1025.e15. https://doi.org/10.1016/j.jaci.2019.11.030

TY - JOUR

T1 - T-cell phenotyping uncovers systemic features of atopic dermatitis and psoriasis

AU - Farrera, Consol

AU - Melchiotti, Rossella

AU - Petrov, Nedyalko

AU - Wei Weng Teng, Karen

AU - Wong, Michael Thomas

AU - Loh, Chiew Yee

AU - Villanova, Federica

AU - Tosi, Isabella

AU - Chen, Jinmiao

AU - Grys, Katarzyna

AU - Sreeneebus, Hemawtee

AU - Chapman, Anna

AU - Perera, Gayathri K.

AU - Heck, Susanne

AU - Gracio, Filipe

AU - de Rinaldis, Emanuele

AU - Barker, Jonathan N.

AU - Smith, Catherine H.

AU - Nestle, Frank O.

AU - Newell, Evan W.

AU - Di Meglio, Paola

PY - 2020/3/1

Y1 - 2020/3/1

N2 - Deep-immunophenotyping of the circulatory T cell compartment using mass cytometry and unsupervised clustering analysis, identifies phenotypic and functional differences in patients with atopic dermatitis (AD) and psoriasis, highlighting the stronger systemic component associated with AD.

AB - Deep-immunophenotyping of the circulatory T cell compartment using mass cytometry and unsupervised clustering analysis, identifies phenotypic and functional differences in patients with atopic dermatitis (AD) and psoriasis, highlighting the stronger systemic component associated with AD.

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U2 - 10.1016/j.jaci.2019.11.030

DO - 10.1016/j.jaci.2019.11.030

M3 - Article

C2 - 31812571

SN - 0091-6749

VL - 145

SP - 1021-1025.e15

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 3

ER -

T-cell phenotyping uncovers systemic features of atopic dermatitis and psoriasis

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