@article{d2bdc22df6024b649672375ec6da9d2e,
title = "Tackling immunosenescence to improve COVID-19 outcomes and vaccine response in older adults",
author = "Cox, {Lynne S.} and Ilaria Bellantuono and Lord, {Janet M.} and Elizabeth Sapey and Mannick, {Joan B.} and Linda Partridge and Gordon, {Adam L.} and Steves, {Claire J.} and Witham, {Miles D.}",
note = "Funding Information: LSC reports grants from Public Health England, Research England (UK SPINE), Elysium Health, Diabetes UK (under the BIRAX programme), the Mellon Longevity Science Programme, and Access Business Group, outside the submitted work; reports personal fees from a Geroscience Masterclass, outside the submitted work; and is an advisor to the All Party Parliamentary Group for Longevity (UK Parliament). IB reports grants from the Biotechnology and Biological Sciences Research Council, Medical Research Council (MRC), Arthritis Research UK, Horizon2020, Cancer Research UK, and the National Centre for the Replacement, Refinement, and Reduction of Animals in Research, outside the submitted work; and reports other support from Novartis, outside the submitted work. JML reports grants from MRC, Versus Arthritis, National Institute for Health Research (NIHR), Scar Free Foundation, Foundation for Research in Rheumatology, Research England (UK SPINE), outside the submitted work; is the Director of the Institute of Inflammation and Ageing, University of Birmingham; and is a special advisor to the House of Lords Science and Technology select committee on Ageing Science, Technology, and Healthy Living. ES reports grants from Health Data Research UK, The Wellcome Trust, MRC, Alpha-1 Foundation, NIHR, British Lung Foundation, outside the submitted work; is the Director of PIONEER, the Health Data Hub in Acute Care at Health Data Research UK; and is the Managing Director of NIHR Clinical Research Facility Birmingham. JBM reports grants from National Institutes of Health (R01AG064802), during the conduct of the study; reports personal fees, non-financial support and other support from resTORbio, outside the submitted work; is employed by resTORbio; and has 14 patent families, which have been filed by Novartis or resTORbio related to RTB101, pending. LP reports grants from The Wellcome Trust and Alzheimer's Research UK, outside the submitted work; reports other support from The Max Planck Society, outside the submitted work; and is the Director of the Max Planck Institute for Biology of Ageing, Cologne. ALG reports grants from NIHR Applied Research Collaboration East Midlands, Dunhill Medical Trust, British Geriatrics Society, Abbeyfield Foundation, the Academy of Medical Sciences, the Newton Fund, and The Wellcome Trust, outside the submitted work. CJS reports grants from The Wellcome Trust and The Chronic Disease Research Foundation, outside the submitted work; and is the clinical and scientific lead on the COVID Symptom Study. MDW reports grants from NIHR Newcastle Biomedical Research Centre, NIHR, British Heart Foundation, Chief Scientist Office of the Scottish Government, British Geriatrics Society, outside the submitted work; and is the National Speciality Lead for Ageing for the NIHR's Clinical Research Network. All authors have jointly submitted a clinical trials bid for COVID-19 prophylaxis to NIHR and continue to work towards establishing clinical trials for improving immunity, COVID vaccine responses, and the overall health of older people. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2020",
month = nov,
doi = "10.1016/S2666-7568(20)30011-8",
language = "English",
volume = "1",
pages = "e55--e57",
journal = "The Lancet Healthy Longevity",
issn = "2666-7568",
publisher = "Elsevier",
number = "2",
}
