Talc Pleurodesis Through Indwelling Pleural Catheters for Malignant Pleural Effusions: Retrospective Case Series of a Novel Clinical Pathway

TY - JOUR

T1 - Talc Pleurodesis Through Indwelling Pleural Catheters for Malignant Pleural Effusions

T2 - Retrospective Case Series of a Novel Clinical Pathway

AU - Ahmed, Liju

AU - Ip, Hugh

AU - Rao, Deepak

AU - Patel, Nishil

AU - Noorzad, Farinaz

PY - 2014/12

Y1 - 2014/12

N2 - Malignant pleural effusions cause significant morbidity, but there is no gold standard minimally invasive treatment. A new therapeutic approach combines talc pleurodesis and indwelling pleural catheters (IPCs) to enable outpatient management. This case series summarizes the safety and efficacy data of all patients (24) with a symptomatic malignant pleural effusion who underwent talc pleurodeses via IPCs between December 2010 and July 2013. Successful pleurodesis was achieved in 22 procedures (92%). There was one empyema, one hydropneumothorax, one recurrent effusion, and two minor complications: one drain site wound infection and one complaint of chest pain. Twenty-two procedures (92%) were performed in the outpatient setting. This report confirms the safety and efficacy of administering talc slurry through IPCs in an outpatient setting. Studies in a larger cohort are necessary to define the role of this novel approach in the treatment algorithm of patients with this condition.

AB - Malignant pleural effusions cause significant morbidity, but there is no gold standard minimally invasive treatment. A new therapeutic approach combines talc pleurodesis and indwelling pleural catheters (IPCs) to enable outpatient management. This case series summarizes the safety and efficacy data of all patients (24) with a symptomatic malignant pleural effusion who underwent talc pleurodeses via IPCs between December 2010 and July 2013. Successful pleurodesis was achieved in 22 procedures (92%). There was one empyema, one hydropneumothorax, one recurrent effusion, and two minor complications: one drain site wound infection and one complaint of chest pain. Twenty-two procedures (92%) were performed in the outpatient setting. This report confirms the safety and efficacy of administering talc slurry through IPCs in an outpatient setting. Studies in a larger cohort are necessary to define the role of this novel approach in the treatment algorithm of patients with this condition.

KW - DISEASE GUIDELINE 2010

KW - SMALL-BORE

KW - MANAGEMENT

KW - OPTIONS

KW - SLURRY

U2 - 10.1378/chest.14-0394

DO - 10.1378/chest.14-0394

M3 - Article

SN - 0012-3692

VL - 146

SP - E190-E194

JO - Chest

JF - Chest

IS - 6

ER -