Targeted Bleeding Management Reduces the Requirements for Blood Component Therapy in Lung Transplant Recipients

Ian Smith*, Bronwyn L. Pearse, Daniel J. Faulke, Rishen Naidoo, Lisa Nicotra, Peter Hopkins, Elizabeth G. Ryan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)

Abstract

Objective: Lung transplantation is associated with high rates of bleeding and frequent blood transfusion. The authors aimed to determine if point-of-care coagulation testing (POCCT) reduced transfusion requirements. Design, Settings, and Participants: A before-and-after cohort analysis conducted at a single tertiary referral center. Ninety-three sequential adult patients between January 2010 and January 2014 undergoing isolated lung transplant without preoperative extracorporeal support were analyzed. Intervention: ROTEM and multi-plate POCCT were introduced on July 1, 2012, with an associated algorithm based on the results. Measurements and Main Results: Statistically significant decreases in the proportion of patients receiving PRBCs (87% . v 65%; p = 0.015), FFP (72% . v 30%; p

Original languageEnglish
JournalJournal of Cardiothoracic and Vascular Anesthesia
DOIs
Publication statusAccepted/In press - 2016

Keywords

  • Blood transfusion
  • Lung transplantation
  • Point-of-care coagulation testing

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