Temporomandibular Disorders and Fibromyalgia Prevalence: A Systematic Review and Meta-Analysis

Pankaew Yakkaphan, Tara Renton, Huann Tan, Priya Thimma ravindranath, Jared Smith, Giorgio Lambru, Pav Chana

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


PURPOSE: To evaluate the prevalence of chronic widespread pain (CWP) and fibromyalgia syndrome (FMS) in TMD patients and the prevalence of TMDs in patients with FMS. METHOD: A systematic search was performed in electronic databases. Studies published in English examining the prevalence of comorbid TMDs and CWP/FMS were included. The Newcastle-Ottawa Scale was used to assess study quality, and meta-analyses using defined diagnostic criteria were conducted to generate pooled prevalence estimates. RESULTS: Nineteen studies of moderate to high quality met the selection criteria. Meta-analyses yielded a pooled prevalence rate (95% CI) for TMDs in FMS patients of 76.8% (69.5% to 83.3%). Myogenous TMDs were more prevalent in FMS patients (63.1%, 47.7% to 77.3%) than disc displacement disorders (24.2%, 19.4% to 39.5%), while a little over 40% of FMS patients had comorbid inflammatory degenerative TMDs (41.8%, 21.9% to 63.2%). Almost a third of individuals (32.7%, 4.5% to 71.0%) with TMDs had comorbid FMS, while estimates of comorbid CWP across studies ranged from 30% to 76%. CONCLUSIONS: Despite variable prevalence rates among the included studies, the present review suggests that TMDs and CWP/FMS frequently coexist, especially for individuals with painful myogenous TMDs. The clinical, pathophysiologic, and therapeutic aspects of this association are important for tailoring appropriate treatment strategies.

Original languageEnglish
Pages (from-to)177-193
Number of pages17
JournalJournal of Oral and Facial Pain and Headache
Issue number3
Publication statusPublished - 17 Nov 2023


Dive into the research topics of 'Temporomandibular Disorders and Fibromyalgia Prevalence: A Systematic Review and Meta-Analysis'. Together they form a unique fingerprint.

Cite this