Terpenoids in Buddleja: relevance to chemosystematics, chemical ecology and biological activity

TY - JOUR

T1 - Terpenoids in Buddleja: relevance to chemosystematics, chemical ecology and biological activity

AU - Houghton, P J

AU - Mensah, A Y

AU - Lessa, N

AU - Hong, L Y

PY - 2003/9

Y1 - 2003/9

N2 - The terpenoids reported from Buddleja species are described. The antifungal activity of chloroform extracts of B. cordala and B. davidii stembark against the soil fungi Fusarium culmorum and Sordari fimicola is reported, with buddledin A shown to be the major compound responsible. The terpenoids present support the view that the Buddlejaceae should be classified in a taxon with Scrophulariaceae rather than Loganiaccae. Ecological aspects of the terpenoids are considered in relation to insects and soil fungi and the role of terpenoids in the chemical basis of the use of Buddleja in traditional medicine is also discussed, especially with regard to their anti-inflammatory properties. (C) 2003 Elsevier Ltd. All rights reserved.

AB - The terpenoids reported from Buddleja species are described. The antifungal activity of chloroform extracts of B. cordala and B. davidii stembark against the soil fungi Fusarium culmorum and Sordari fimicola is reported, with buddledin A shown to be the major compound responsible. The terpenoids present support the view that the Buddlejaceae should be classified in a taxon with Scrophulariaceae rather than Loganiaccae. Ecological aspects of the terpenoids are considered in relation to insects and soil fungi and the role of terpenoids in the chemical basis of the use of Buddleja in traditional medicine is also discussed, especially with regard to their anti-inflammatory properties. (C) 2003 Elsevier Ltd. All rights reserved.

U2 - 10.1016/S0031-9422(03)00264-4

DO - 10.1016/S0031-9422(03)00264-4

M3 - Literature review

VL - 64

SP - 385

EP - 393

JO - PHYTOCHEMISTRY

JF - PHYTOCHEMISTRY

IS - 2

ER -