The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 Patients

Alessandra Borlotti; Helena Thomaides-Brears; Georgios Georgiopoulos; Rajarshi Banerjee; Matthew D Robson; Dahlene N Fusco; Pier-Giorgio Masci

doi:10.3389/fcvm.2022.854750

The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 Patients

Alessandra Borlotti, Helena Thomaides-Brears, Georgios Georgiopoulos, Rajarshi Banerjee, Matthew D Robson, Dahlene N Fusco, Pier-Giorgio Masci

Research output: Contribution to journal › Review article › peer-review

Abstract

In COVID-19 the development of severe viral pneumonia that is coupled with systemic inflammatory response triggers multi-organ failure and is of major concern. Cardiac involvement occurs in nearly 60% of patients with pre-existing cardiovascular conditions and heralds worse clinical outcome. Diagnoses carried out in the acute phase of COVID-19 rely upon increased levels of circulating cardiac injury biomarkers and transthoracic echocardiography. These diagnostics, however, were unable to pinpoint the mechanisms of cardiac injury in COVID-19 patients. Identifying the main features of cardiac injury remains an urgent yet unmet need in cardiology, given the potential clinical consequences. Cardiovascular magnetic resonance (CMR) provides an unparalleled opportunity to gain a deeper insight into myocardial injury given its unique ability to interrogate the properties of myocardial tissue. This endeavor is particularly important in convalescent COVID-19 patients as many continue to experience chest pain, palpitations, dyspnea and exertional fatigue, six or more months after the acute illness. This review will provide a critical appraisal of research on cardiovascular damage in convalescent adult COVID-19 patients with an emphasis on the use of CMR and its value to our understanding of organ damage.

Original language	English
Pages (from-to)	854750
Journal	Frontiers in Cardiovascular Medicine
Volume	9
DOIs	https://doi.org/10.3389/fcvm.2022.854750
Publication status	Published - 2022

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title = "The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 Patients",

abstract = "In COVID-19 the development of severe viral pneumonia that is coupled with systemic inflammatory response triggers multi-organ failure and is of major concern. Cardiac involvement occurs in nearly 60% of patients with pre-existing cardiovascular conditions and heralds worse clinical outcome. Diagnoses carried out in the acute phase of COVID-19 rely upon increased levels of circulating cardiac injury biomarkers and transthoracic echocardiography. These diagnostics, however, were unable to pinpoint the mechanisms of cardiac injury in COVID-19 patients. Identifying the main features of cardiac injury remains an urgent yet unmet need in cardiology, given the potential clinical consequences. Cardiovascular magnetic resonance (CMR) provides an unparalleled opportunity to gain a deeper insight into myocardial injury given its unique ability to interrogate the properties of myocardial tissue. This endeavor is particularly important in convalescent COVID-19 patients as many continue to experience chest pain, palpitations, dyspnea and exertional fatigue, six or more months after the acute illness. This review will provide a critical appraisal of research on cardiovascular damage in convalescent adult COVID-19 patients with an emphasis on the use of CMR and its value to our understanding of organ damage.",

author = "Alessandra Borlotti and Helena Thomaides-Brears and Georgios Georgiopoulos and Rajarshi Banerjee and Robson, {Matthew D} and Fusco, {Dahlene N} and Pier-Giorgio Masci",

note = "Copyright {\textcopyright} 2022 Borlotti, Thomaides-Brears, Georgiopoulos, Banerjee, Robson, Fusco and Masci.",

year = "2022",

doi = "10.3389/fcvm.2022.854750",

language = "English",

volume = "9",

pages = "854750",

journal = "Frontiers in Cardiovascular Medicine",

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T1 - The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 Patients

AU - Borlotti, Alessandra

AU - Thomaides-Brears, Helena

AU - Georgiopoulos, Georgios

AU - Banerjee, Rajarshi

AU - Robson, Matthew D

AU - Fusco, Dahlene N

AU - Masci, Pier-Giorgio

PY - 2022

Y1 - 2022

N2 - In COVID-19 the development of severe viral pneumonia that is coupled with systemic inflammatory response triggers multi-organ failure and is of major concern. Cardiac involvement occurs in nearly 60% of patients with pre-existing cardiovascular conditions and heralds worse clinical outcome. Diagnoses carried out in the acute phase of COVID-19 rely upon increased levels of circulating cardiac injury biomarkers and transthoracic echocardiography. These diagnostics, however, were unable to pinpoint the mechanisms of cardiac injury in COVID-19 patients. Identifying the main features of cardiac injury remains an urgent yet unmet need in cardiology, given the potential clinical consequences. Cardiovascular magnetic resonance (CMR) provides an unparalleled opportunity to gain a deeper insight into myocardial injury given its unique ability to interrogate the properties of myocardial tissue. This endeavor is particularly important in convalescent COVID-19 patients as many continue to experience chest pain, palpitations, dyspnea and exertional fatigue, six or more months after the acute illness. This review will provide a critical appraisal of research on cardiovascular damage in convalescent adult COVID-19 patients with an emphasis on the use of CMR and its value to our understanding of organ damage.

AB - In COVID-19 the development of severe viral pneumonia that is coupled with systemic inflammatory response triggers multi-organ failure and is of major concern. Cardiac involvement occurs in nearly 60% of patients with pre-existing cardiovascular conditions and heralds worse clinical outcome. Diagnoses carried out in the acute phase of COVID-19 rely upon increased levels of circulating cardiac injury biomarkers and transthoracic echocardiography. These diagnostics, however, were unable to pinpoint the mechanisms of cardiac injury in COVID-19 patients. Identifying the main features of cardiac injury remains an urgent yet unmet need in cardiology, given the potential clinical consequences. Cardiovascular magnetic resonance (CMR) provides an unparalleled opportunity to gain a deeper insight into myocardial injury given its unique ability to interrogate the properties of myocardial tissue. This endeavor is particularly important in convalescent COVID-19 patients as many continue to experience chest pain, palpitations, dyspnea and exertional fatigue, six or more months after the acute illness. This review will provide a critical appraisal of research on cardiovascular damage in convalescent adult COVID-19 patients with an emphasis on the use of CMR and its value to our understanding of organ damage.

U2 - 10.3389/fcvm.2022.854750

DO - 10.3389/fcvm.2022.854750

M3 - Review article

C2 - 35463767

SN - 2297-055X

VL - 9

SP - 854750

JO - Frontiers in Cardiovascular Medicine

JF - Frontiers in Cardiovascular Medicine

ER -

The Additive Value of Cardiovascular Magnetic Resonance in Convalescent COVID-19 Patients

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