TY - JOUR
T1 - The additive value of three-dimensional derived left atrial volume and carotid imaging in dobutamine stress echocardiography
AU - Sachpekidis, Vasileios
AU - Bhan, Amit
AU - Paul, Matthias
AU - Gianstefani, Silvia
AU - Smith, Lindsay
AU - Reiken, Joseph
AU - Walker, Nicola
AU - Harries, Derek
AU - Pearson, Peter
AU - Monaghan, Mark J.
PY - 2011/1
Y1 - 2011/1
N2 - Aims To evaluate whether the three-dimensional (3D) left atrial volume index (LAVI) and/or the presence of carotid plaques (CP) can predict the result of dobutamine stress echocardiography (DSE), thereby aiding interpretation.
Methods and results We studied 130 patients (52 male, mean age 63 +/- 11 years) with normal resting wall motion (WM) undergoing DSE. All patients had the end-systolic 2D and 3D LAVI measured, as well as bilateral carotid scanning. DSE was reported as abnormal in 50 (38.5%) patients. 3D end-systolic LAVI measurements were significantly higher (31.5 +/- 8.2 vs 27.4 +/- 7.4 mL/m(2), P = 0.004) in those with an abnormal DSE. The two groups did not differ significantly on the 2D derived maximum LAVI measurements (36.2 +/- 9.5 vs 34.2 +/- 11.2, P = 0.299) and the presence of plaques in the carotid arteries (89.1 vs. 76.2%, P = 0.100). Receiver operating characteristic curves were created to define cut-offs that could predict the DSE result for the 3D LAVI. A 3D LAVI of >24.5 mL/m(2) had a sensitivity of 80% for predicting an abnormal DSE, whereas a value of >36.0 mL/m(2) had a specificity of 93% for the same cause. Intra-observer (r = 0.997, P <0.0001) and inter-observer (r = 0.961, P <0.0001) variability for 3D LAVI measurements was found to be excellent.
Conclusion Three-dimensional (but not 2D) assessment of LAVI may offer additional information in predicting the result of DSE. Carotid scanning did not offer additional information for the same cause.
AB - Aims To evaluate whether the three-dimensional (3D) left atrial volume index (LAVI) and/or the presence of carotid plaques (CP) can predict the result of dobutamine stress echocardiography (DSE), thereby aiding interpretation.
Methods and results We studied 130 patients (52 male, mean age 63 +/- 11 years) with normal resting wall motion (WM) undergoing DSE. All patients had the end-systolic 2D and 3D LAVI measured, as well as bilateral carotid scanning. DSE was reported as abnormal in 50 (38.5%) patients. 3D end-systolic LAVI measurements were significantly higher (31.5 +/- 8.2 vs 27.4 +/- 7.4 mL/m(2), P = 0.004) in those with an abnormal DSE. The two groups did not differ significantly on the 2D derived maximum LAVI measurements (36.2 +/- 9.5 vs 34.2 +/- 11.2, P = 0.299) and the presence of plaques in the carotid arteries (89.1 vs. 76.2%, P = 0.100). Receiver operating characteristic curves were created to define cut-offs that could predict the DSE result for the 3D LAVI. A 3D LAVI of >24.5 mL/m(2) had a sensitivity of 80% for predicting an abnormal DSE, whereas a value of >36.0 mL/m(2) had a specificity of 93% for the same cause. Intra-observer (r = 0.997, P <0.0001) and inter-observer (r = 0.961, P <0.0001) variability for 3D LAVI measurements was found to be excellent.
Conclusion Three-dimensional (but not 2D) assessment of LAVI may offer additional information in predicting the result of DSE. Carotid scanning did not offer additional information for the same cause.
U2 - 10.1093/ejechocard/jeq104
DO - 10.1093/ejechocard/jeq104
M3 - Article
VL - 12
SP - 46
EP - 53
JO - European Journal of Echocardiography
JF - European Journal of Echocardiography
IS - 1
ER -
