King's College London

Research portal

The Association Between Parental Migraine and Infant Colic: A Cross-Sectional, Web-Based, U.S. Survey Study

Research output: Contribution to journalArticle

Standard

The Association Between Parental Migraine and Infant Colic : A Cross-Sectional, Web-Based, U.S. Survey Study. / Gelfand, Amy A.; Buse, Dawn C.; Cabana, Michael D.; Grimes, Barbara; Goadsby, Peter J.; Allen, I. Elaine.

In: Headache, Vol. 59, No. 7, 07.2019, p. 988-1001.

Research output: Contribution to journalArticle

Harvard

Gelfand, AA, Buse, DC, Cabana, MD, Grimes, B, Goadsby, PJ & Allen, IE 2019, 'The Association Between Parental Migraine and Infant Colic: A Cross-Sectional, Web-Based, U.S. Survey Study', Headache, vol. 59, no. 7, pp. 988-1001. https://doi.org/10.1111/head.13575

APA

Gelfand, A. A., Buse, D. C., Cabana, M. D., Grimes, B., Goadsby, P. J., & Allen, I. E. (2019). The Association Between Parental Migraine and Infant Colic: A Cross-Sectional, Web-Based, U.S. Survey Study. Headache, 59(7), 988-1001. https://doi.org/10.1111/head.13575

Vancouver

Gelfand AA, Buse DC, Cabana MD, Grimes B, Goadsby PJ, Allen IE. The Association Between Parental Migraine and Infant Colic: A Cross-Sectional, Web-Based, U.S. Survey Study. Headache. 2019 Jul;59(7):988-1001. https://doi.org/10.1111/head.13575

Author

Gelfand, Amy A. ; Buse, Dawn C. ; Cabana, Michael D. ; Grimes, Barbara ; Goadsby, Peter J. ; Allen, I. Elaine. / The Association Between Parental Migraine and Infant Colic : A Cross-Sectional, Web-Based, U.S. Survey Study. In: Headache. 2019 ; Vol. 59, No. 7. pp. 988-1001.

Bibtex Download

@article{c09f1c8392ad410992b609599b3a1883,
title = "The Association Between Parental Migraine and Infant Colic: A Cross-Sectional, Web-Based, U.S. Survey Study",
abstract = "Background: Infant colic, or excessive crying in an otherwise healthy infant, is common, although the cause(s) are not known. This study aimed to determine whether parental migraine is associated with infant colic. Methods: This was a cross-sectional online survey study of biological parents of 4-8 week olds in the United States during February and March 2017 and October 2017-April 2018. Parents self-reported information about their and their infant's health using validated instruments wherever possible. Parents were recruited using social media advertisements and completed the survey online. Migraine was identified with a validated screener using modified International Classification of Headache Disorders 3rd edition criteria. Parental depression and anxiety were screened with the Patient Health Questionnaire-2 (PHQ-2) and Generalized Anxiety Disorder Scale-2 (GAD-2). Parental seasonal allergies and asthma were assessed by self-report. Infant colic was determined based on parental response to the question, “Has your baby cried for at least 3 hours on at least 3 days in the last week?”. Results: A total of 1,715 surveys were completed over 2 recruitment periods; 1,419 formed the analysis set. Eight hundred twenty-seven were completed by biological mothers and 592 by biological fathers. Mean (SD) maternal age: 28.9 (5.1) years; 33.5% had migraine/probable migraine. Maternal migraine was associated with increased odds of infant colic: OR 1.7 (1.3-2.4). Among mothers with migraine, headache frequency ≥15 days/month was associated with higher risk of infant colic (OR 2.5 (1.2-5.3)); and anxiety was borderline associated (OR 1.7 (1.0-2.9)). Mean (SD) paternal age was 31.6 (4.5) years; 20.8% had migraine/probable migraine. Paternal migraine was not associated with infant colic: OR 1.0 (0.7-1.5). Fathers with depression (OR 2.4 (1.4-4.3)) or anxiety (OR 1.7 (1.1-2.7)) were more likely to have a baby with colic but having a girl infant was protective: (OR 0.7 (0.5-0.97)). Conclusions: Mothers with migraine are more likely to have a baby with colic, while fathers with migraine are not. Further research is needed to determine the mechanisms underlying these findings. In the meantime, clinicians may wish to counsel parents with a maternal history of migraine about the increased possibility of having a colicky infant and provide resources and education about infant crying.",
keywords = "anxiety, depression, infant colic, migraine",
author = "Gelfand, {Amy A.} and Buse, {Dawn C.} and Cabana, {Michael D.} and Barbara Grimes and Goadsby, {Peter J.} and Allen, {I. Elaine}",
year = "2019",
month = jul,
doi = "10.1111/head.13575",
language = "English",
volume = "59",
pages = "988--1001",
journal = "Headache",
issn = "0017-8748",
publisher = "Wiley-Blackwell",
number = "7",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - The Association Between Parental Migraine and Infant Colic

T2 - A Cross-Sectional, Web-Based, U.S. Survey Study

AU - Gelfand, Amy A.

AU - Buse, Dawn C.

AU - Cabana, Michael D.

AU - Grimes, Barbara

AU - Goadsby, Peter J.

AU - Allen, I. Elaine

PY - 2019/7

Y1 - 2019/7

N2 - Background: Infant colic, or excessive crying in an otherwise healthy infant, is common, although the cause(s) are not known. This study aimed to determine whether parental migraine is associated with infant colic. Methods: This was a cross-sectional online survey study of biological parents of 4-8 week olds in the United States during February and March 2017 and October 2017-April 2018. Parents self-reported information about their and their infant's health using validated instruments wherever possible. Parents were recruited using social media advertisements and completed the survey online. Migraine was identified with a validated screener using modified International Classification of Headache Disorders 3rd edition criteria. Parental depression and anxiety were screened with the Patient Health Questionnaire-2 (PHQ-2) and Generalized Anxiety Disorder Scale-2 (GAD-2). Parental seasonal allergies and asthma were assessed by self-report. Infant colic was determined based on parental response to the question, “Has your baby cried for at least 3 hours on at least 3 days in the last week?”. Results: A total of 1,715 surveys were completed over 2 recruitment periods; 1,419 formed the analysis set. Eight hundred twenty-seven were completed by biological mothers and 592 by biological fathers. Mean (SD) maternal age: 28.9 (5.1) years; 33.5% had migraine/probable migraine. Maternal migraine was associated with increased odds of infant colic: OR 1.7 (1.3-2.4). Among mothers with migraine, headache frequency ≥15 days/month was associated with higher risk of infant colic (OR 2.5 (1.2-5.3)); and anxiety was borderline associated (OR 1.7 (1.0-2.9)). Mean (SD) paternal age was 31.6 (4.5) years; 20.8% had migraine/probable migraine. Paternal migraine was not associated with infant colic: OR 1.0 (0.7-1.5). Fathers with depression (OR 2.4 (1.4-4.3)) or anxiety (OR 1.7 (1.1-2.7)) were more likely to have a baby with colic but having a girl infant was protective: (OR 0.7 (0.5-0.97)). Conclusions: Mothers with migraine are more likely to have a baby with colic, while fathers with migraine are not. Further research is needed to determine the mechanisms underlying these findings. In the meantime, clinicians may wish to counsel parents with a maternal history of migraine about the increased possibility of having a colicky infant and provide resources and education about infant crying.

AB - Background: Infant colic, or excessive crying in an otherwise healthy infant, is common, although the cause(s) are not known. This study aimed to determine whether parental migraine is associated with infant colic. Methods: This was a cross-sectional online survey study of biological parents of 4-8 week olds in the United States during February and March 2017 and October 2017-April 2018. Parents self-reported information about their and their infant's health using validated instruments wherever possible. Parents were recruited using social media advertisements and completed the survey online. Migraine was identified with a validated screener using modified International Classification of Headache Disorders 3rd edition criteria. Parental depression and anxiety were screened with the Patient Health Questionnaire-2 (PHQ-2) and Generalized Anxiety Disorder Scale-2 (GAD-2). Parental seasonal allergies and asthma were assessed by self-report. Infant colic was determined based on parental response to the question, “Has your baby cried for at least 3 hours on at least 3 days in the last week?”. Results: A total of 1,715 surveys were completed over 2 recruitment periods; 1,419 formed the analysis set. Eight hundred twenty-seven were completed by biological mothers and 592 by biological fathers. Mean (SD) maternal age: 28.9 (5.1) years; 33.5% had migraine/probable migraine. Maternal migraine was associated with increased odds of infant colic: OR 1.7 (1.3-2.4). Among mothers with migraine, headache frequency ≥15 days/month was associated with higher risk of infant colic (OR 2.5 (1.2-5.3)); and anxiety was borderline associated (OR 1.7 (1.0-2.9)). Mean (SD) paternal age was 31.6 (4.5) years; 20.8% had migraine/probable migraine. Paternal migraine was not associated with infant colic: OR 1.0 (0.7-1.5). Fathers with depression (OR 2.4 (1.4-4.3)) or anxiety (OR 1.7 (1.1-2.7)) were more likely to have a baby with colic but having a girl infant was protective: (OR 0.7 (0.5-0.97)). Conclusions: Mothers with migraine are more likely to have a baby with colic, while fathers with migraine are not. Further research is needed to determine the mechanisms underlying these findings. In the meantime, clinicians may wish to counsel parents with a maternal history of migraine about the increased possibility of having a colicky infant and provide resources and education about infant crying.

KW - anxiety

KW - depression

KW - infant colic

KW - migraine

UR - http://www.scopus.com/inward/record.url?scp=85068145268&partnerID=8YFLogxK

U2 - 10.1111/head.13575

DO - 10.1111/head.13575

M3 - Article

AN - SCOPUS:85068145268

VL - 59

SP - 988

EP - 1001

JO - Headache

JF - Headache

SN - 0017-8748

IS - 7

ER -

View graph of relations

© 2020 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454