TY - JOUR
T1 - The autism diagnostic observation schedule
T2 - Patterns in individuals with anorexia nervosa
AU - Bentz, Mette
AU - Westwood, Heather
AU - Jepsen, Jens Richardt Møllegaard
AU - Plessen, Kerstin Jessica
AU - Tchanturia, Kate
PY - 2020/9/1
Y1 - 2020/9/1
N2 - Objective: Studies have used the Autism Diagnostic Observation Schedule (the ADOS-2) in individuals with anorexia nervosa (AN), but the patterns of scores have not been assessed. We examined which subset of the ADOS-2 items best discriminate individuals with AN from healthy controls (HC), and assessed the potential clustering of AN participants based on different profiles of the ADOS-2 item scores. Method: We combined datasets from two previous studies, and (a) compared mean ranks between young AN participants (N = 118) and HC (N = 42), (ii) replicated the item selection procedure of the existing ADOS-2 algorithm to assess sensitivity of items in the AN group, and (c) applied a two-step clustering analysis in the AN group (N = 149). Results: AN participants displayed significantly higher mean ranks than HC participants in five of 32 items. All five items are part of the existing ADOS-2 algorithm. We found two clusters of AN participants; one representing normal social behaviour, comprising 68% of the individuals with AN, and one representing less efficient social behaviour, comprising 32% of individuals with AN. Conclusions: The items comprising the social affective cluster of the existing ADOS-2 algorithm are well suited to assess difficulties with social functioning in individuals with AN.
AB - Objective: Studies have used the Autism Diagnostic Observation Schedule (the ADOS-2) in individuals with anorexia nervosa (AN), but the patterns of scores have not been assessed. We examined which subset of the ADOS-2 items best discriminate individuals with AN from healthy controls (HC), and assessed the potential clustering of AN participants based on different profiles of the ADOS-2 item scores. Method: We combined datasets from two previous studies, and (a) compared mean ranks between young AN participants (N = 118) and HC (N = 42), (ii) replicated the item selection procedure of the existing ADOS-2 algorithm to assess sensitivity of items in the AN group, and (c) applied a two-step clustering analysis in the AN group (N = 149). Results: AN participants displayed significantly higher mean ranks than HC participants in five of 32 items. All five items are part of the existing ADOS-2 algorithm. We found two clusters of AN participants; one representing normal social behaviour, comprising 68% of the individuals with AN, and one representing less efficient social behaviour, comprising 32% of individuals with AN. Conclusions: The items comprising the social affective cluster of the existing ADOS-2 algorithm are well suited to assess difficulties with social functioning in individuals with AN.
KW - anorexia nervosa
KW - autism spectrum disorder
KW - psychometrics
KW - social functioning
UR - http://www.scopus.com/inward/record.url?scp=85088809393&partnerID=8YFLogxK
U2 - 10.1002/erv.2757
DO - 10.1002/erv.2757
M3 - Article
AN - SCOPUS:85088809393
SN - 1072-4133
VL - 28
SP - 571
EP - 579
JO - European Eating Disorders Review
JF - European Eating Disorders Review
IS - 5
ER -