The autism diagnostic observation schedule: Revised algorithms for improved diagnostic validity

Katherine Gotham, Susan Risi, Andrew Pickles, Catherine Lord

Research output: Contribution to journalArticlepeer-review

890 Citations (Scopus)

Abstract

Autism Diagnostic Observation Schedule (ADOS) Modules 1-3 item and domain total distributions were reviewed for 1,630 assessments of children aged 14 months to 16 years with an autism spectrum disorder (ASD) or with heterogeneous non-spectrum disorders. Children were divided by language level and age to yield more homogeneous cells. Items were chosen that best differentiated between diagnoses and were arranged into domains on the basis of multi-factor item-response analysis. Reflecting recent research, the revised algorithm now consists of two new domains, Social Affect and Restricted, Repetitive Behaviors (RRB), combined to one score to which thresholds are applied, resulting in generally improved predictive value.

Original languageEnglish
Pages (from-to)613-627
Number of pages15
JournalJournal of Autism and Developmental Disorders
Volume37
Issue number4
DOIs
Publication statusPublished - Apr 2007

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