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The developmental trajectory of disruptive behavior in Down syndrome, fragile X syndrome, Prader-Willi syndrome and Williams syndrome

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The developmental trajectory of disruptive behavior in Down syndrome, fragile X syndrome, Prader-Willi syndrome and Williams syndrome. / Rice, Lauren J.; Gray, Kylie M.; Howlin, Patricia; Taffe, John; Tonge, Bruce J.; Einfeld, Stewart L.

In: American Journal of Medical Genetics. Part C: Seminars in Medical Genetics, Vol. 169, No. 2, 15.05.2015, p. 182-187.

Research output: Contribution to journalArticle

Harvard

Rice, LJ, Gray, KM, Howlin, P, Taffe, J, Tonge, BJ & Einfeld, SL 2015, 'The developmental trajectory of disruptive behavior in Down syndrome, fragile X syndrome, Prader-Willi syndrome and Williams syndrome', American Journal of Medical Genetics. Part C: Seminars in Medical Genetics, vol. 169, no. 2, pp. 182-187. https://doi.org/10.1002/ajmg.c.31442

APA

Rice, L. J., Gray, K. M., Howlin, P., Taffe, J., Tonge, B. J., & Einfeld, S. L. (2015). The developmental trajectory of disruptive behavior in Down syndrome, fragile X syndrome, Prader-Willi syndrome and Williams syndrome. American Journal of Medical Genetics. Part C: Seminars in Medical Genetics, 169(2), 182-187. https://doi.org/10.1002/ajmg.c.31442

Vancouver

Rice LJ, Gray KM, Howlin P, Taffe J, Tonge BJ, Einfeld SL. The developmental trajectory of disruptive behavior in Down syndrome, fragile X syndrome, Prader-Willi syndrome and Williams syndrome. American Journal of Medical Genetics. Part C: Seminars in Medical Genetics. 2015 May 15;169(2):182-187. https://doi.org/10.1002/ajmg.c.31442

Author

Rice, Lauren J. ; Gray, Kylie M. ; Howlin, Patricia ; Taffe, John ; Tonge, Bruce J. ; Einfeld, Stewart L. / The developmental trajectory of disruptive behavior in Down syndrome, fragile X syndrome, Prader-Willi syndrome and Williams syndrome. In: American Journal of Medical Genetics. Part C: Seminars in Medical Genetics. 2015 ; Vol. 169, No. 2. pp. 182-187.

Bibtex Download

@article{0b2315ce5991447b98bb45326decf6f6,
title = "The developmental trajectory of disruptive behavior in Down syndrome, fragile X syndrome, Prader-Willi syndrome and Williams syndrome",
abstract = "The aim of this study was to investigate the developmental trajectories of verbal aggression, physical aggression, and temper tantrums in four genetic syndrome groups. Participants were part of the Australian Child to Adult Development Study (ACAD), which collected information from a cohort of individuals with an intellectual disability at five time points over 18 years. Data were examined from a total of 248 people with one of the four following syndromes: Down syndrome, Fragile X syndrome, Prader-Willi syndrome, or Williams syndrome. Changes in behaviors were measured using validated items from the Developmental Behavior Checklist (DBC). The results indicate that, while verbal aggression shows no evidence of diminishing with age, physical aggression, and temper tantrums decline with age before 19 years for people with Down syndrome, Fragile X syndrome, and William syndrome; and after 19 years for people with Prader-Willi syndrome. These findings offer a somewhat more optimistic outlook for people with an intellectual disability than has previously been suggested. Research is needed to investigate the mechanisms predisposing people with PWS to persistence of temper tantrums and physical aggression into adulthood.",
keywords = "Developmental trajectory, Down syndrome, Fragile X syndrome, Prader-Willi syndrome, Williams syndrome",
author = "Rice, {Lauren J.} and Gray, {Kylie M.} and Patricia Howlin and John Taffe and Tonge, {Bruce J.} and Einfeld, {Stewart L.}",
year = "2015",
month = may,
day = "15",
doi = "10.1002/ajmg.c.31442",
language = "English",
volume = "169",
pages = "182--187",
journal = "American Journal of Medical Genetics. Part C: Seminars in Medical Genetics",
issn = "1552-4868",
publisher = "Wiley-Liss Inc.",
number = "2",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - The developmental trajectory of disruptive behavior in Down syndrome, fragile X syndrome, Prader-Willi syndrome and Williams syndrome

AU - Rice, Lauren J.

AU - Gray, Kylie M.

AU - Howlin, Patricia

AU - Taffe, John

AU - Tonge, Bruce J.

AU - Einfeld, Stewart L.

PY - 2015/5/15

Y1 - 2015/5/15

N2 - The aim of this study was to investigate the developmental trajectories of verbal aggression, physical aggression, and temper tantrums in four genetic syndrome groups. Participants were part of the Australian Child to Adult Development Study (ACAD), which collected information from a cohort of individuals with an intellectual disability at five time points over 18 years. Data were examined from a total of 248 people with one of the four following syndromes: Down syndrome, Fragile X syndrome, Prader-Willi syndrome, or Williams syndrome. Changes in behaviors were measured using validated items from the Developmental Behavior Checklist (DBC). The results indicate that, while verbal aggression shows no evidence of diminishing with age, physical aggression, and temper tantrums decline with age before 19 years for people with Down syndrome, Fragile X syndrome, and William syndrome; and after 19 years for people with Prader-Willi syndrome. These findings offer a somewhat more optimistic outlook for people with an intellectual disability than has previously been suggested. Research is needed to investigate the mechanisms predisposing people with PWS to persistence of temper tantrums and physical aggression into adulthood.

AB - The aim of this study was to investigate the developmental trajectories of verbal aggression, physical aggression, and temper tantrums in four genetic syndrome groups. Participants were part of the Australian Child to Adult Development Study (ACAD), which collected information from a cohort of individuals with an intellectual disability at five time points over 18 years. Data were examined from a total of 248 people with one of the four following syndromes: Down syndrome, Fragile X syndrome, Prader-Willi syndrome, or Williams syndrome. Changes in behaviors were measured using validated items from the Developmental Behavior Checklist (DBC). The results indicate that, while verbal aggression shows no evidence of diminishing with age, physical aggression, and temper tantrums decline with age before 19 years for people with Down syndrome, Fragile X syndrome, and William syndrome; and after 19 years for people with Prader-Willi syndrome. These findings offer a somewhat more optimistic outlook for people with an intellectual disability than has previously been suggested. Research is needed to investigate the mechanisms predisposing people with PWS to persistence of temper tantrums and physical aggression into adulthood.

KW - Developmental trajectory

KW - Down syndrome

KW - Fragile X syndrome

KW - Prader-Willi syndrome

KW - Williams syndrome

UR - http://www.scopus.com/inward/record.url?scp=84930741556&partnerID=8YFLogxK

U2 - 10.1002/ajmg.c.31442

DO - 10.1002/ajmg.c.31442

M3 - Article

AN - SCOPUS:84930741556

VL - 169

SP - 182

EP - 187

JO - American Journal of Medical Genetics. Part C: Seminars in Medical Genetics

JF - American Journal of Medical Genetics. Part C: Seminars in Medical Genetics

SN - 1552-4868

IS - 2

ER -

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