The effect of casein and calcium containing paste on plaque pH following a subsequent carbohydrate challenge

TY - JOUR

T1 - The effect of casein and calcium containing paste on plaque pH following a subsequent carbohydrate challenge

AU - Caruana, Paul Chetcuti

AU - Al Mulaify, Sami

AU - Moazzez, Rebecca

AU - Bartlett, David

PY - 2009/7

Y1 - 2009/7

N2 - Objectives: Previous research has shown that regular use of CPP-ACP increases calcium and inorganic phosphates in plaque and reduces enamel mineral loss. The aim of this study was to investigate if a CPP-ACP-containing paste would neutralize acidic challenges in dental plaque following sucrose rinse.Method: Plaque pH was measured on 15 subjects in a cross-over study with and without prior application of the paste and with and without CPP-ACP. On each occasion, subjects rinsed with 10% sucrose and sorbitol solutions for 2 min in randomized order.Results: The results showed the median lowest pH without paste was 4.8 (IQR: 4.7-5.0) and with mousse 5.6 (IQR: 5.5-5.6 and p <0.001). The median lowest pH was 5.0 (IQR: 4.9-5.3) without CPP-ACP and with CPP-ACP was 5.8 (5.6-6.1 and p <0.001). The time that pH remained below 5.7 and the time to return to resting pH showed similar differences in all subjects (p <0.01).Conclusion: The results indicate that prior application of a CPP-ACP-containing paste reduced the fall in plaque pH following a sucrose challenge.

AB - Objectives: Previous research has shown that regular use of CPP-ACP increases calcium and inorganic phosphates in plaque and reduces enamel mineral loss. The aim of this study was to investigate if a CPP-ACP-containing paste would neutralize acidic challenges in dental plaque following sucrose rinse.Method: Plaque pH was measured on 15 subjects in a cross-over study with and without prior application of the paste and with and without CPP-ACP. On each occasion, subjects rinsed with 10% sucrose and sorbitol solutions for 2 min in randomized order.Results: The results showed the median lowest pH without paste was 4.8 (IQR: 4.7-5.0) and with mousse 5.6 (IQR: 5.5-5.6 and p <0.001). The median lowest pH was 5.0 (IQR: 4.9-5.3) without CPP-ACP and with CPP-ACP was 5.8 (5.6-6.1 and p <0.001). The time that pH remained below 5.7 and the time to return to resting pH showed similar differences in all subjects (p <0.01).Conclusion: The results indicate that prior application of a CPP-ACP-containing paste reduced the fall in plaque pH following a sucrose challenge.

U2 - 10.1016/j.jdent.2009.03.010

DO - 10.1016/j.jdent.2009.03.010

M3 - Article

SN - 1879-176X

VL - 37

SP - 522

EP - 526

JO - Journal of Dentistry

JF - Journal of Dentistry

IS - 7

ER -