The effect of obesity on orofacial pain during early orthodontic treatment with fixed appliances: A prospective cohort study

TY - JOUR

T1 - The effect of obesity on orofacial pain during early orthodontic treatment with fixed appliances

T2 - A prospective cohort study

AU - Saloom, Hayder F.

AU - Papageorgiou, Spyridon N.

AU - Carpenter, Guy H.

AU - Cobourne, Martyn T.

PY - 2018/7/27

Y1 - 2018/7/27

N2 - Introduction We have investigated orofacial pain in a prospective cohort of obese and normal-weight subjects undergoing fixed-appliance orthodontic treatment. Methods Fifty-five subjects (27 males, 28 females) mean age 15.1 (1.6) years and mean body mass index 30.2 (3.5) in obese and 19.4 (2.2) kg/m2 in normal-weight groups were followed for 1 week after appliance placement. Primary outcome was maximum-pain measured using a 100-mm visual analogue scale. Secondary outcomes included mean pain and oral analgesic consumption. Results Mean maximum pain for the total sample was 73.7 (standard deviation 14.8; 95% confidence interval 69.8-77.7) mm with no significant differences among groups (P = 0.247). However, mean maximum pain was higher at all time-points for the obese group and significant at 72 hours (P = 0.034). Total analgesia consumed by the obese group was also significantly higher than normal weight (P = 0.041). Multivariable regression found the only significant predictor for mean pain was time. After adjusting for confounding, obesity was associated with higher (+4.47 mm) mean pain at each time-point (P = 0.018). A significant association existed between obesity and total analgesic consumption (univariable-analysis, P = 0.035; multivariable analysis, P = 0.023). After accounting for confounders, obese patients were associated with taking a higher quantity of oral analgesics. Conclusions We found a trend towards increased mean pain and an association with increased analgesic consumption in obese subjects during the first week following fixed-appliance placement.

AB - Introduction We have investigated orofacial pain in a prospective cohort of obese and normal-weight subjects undergoing fixed-appliance orthodontic treatment. Methods Fifty-five subjects (27 males, 28 females) mean age 15.1 (1.6) years and mean body mass index 30.2 (3.5) in obese and 19.4 (2.2) kg/m2 in normal-weight groups were followed for 1 week after appliance placement. Primary outcome was maximum-pain measured using a 100-mm visual analogue scale. Secondary outcomes included mean pain and oral analgesic consumption. Results Mean maximum pain for the total sample was 73.7 (standard deviation 14.8; 95% confidence interval 69.8-77.7) mm with no significant differences among groups (P = 0.247). However, mean maximum pain was higher at all time-points for the obese group and significant at 72 hours (P = 0.034). Total analgesia consumed by the obese group was also significantly higher than normal weight (P = 0.041). Multivariable regression found the only significant predictor for mean pain was time. After adjusting for confounding, obesity was associated with higher (+4.47 mm) mean pain at each time-point (P = 0.018). A significant association existed between obesity and total analgesic consumption (univariable-analysis, P = 0.035; multivariable analysis, P = 0.023). After accounting for confounders, obese patients were associated with taking a higher quantity of oral analgesics. Conclusions We found a trend towards increased mean pain and an association with increased analgesic consumption in obese subjects during the first week following fixed-appliance placement.

UR - http://www.scopus.com/inward/record.url?scp=85051001232&partnerID=8YFLogxK

U2 - 10.1093/ejo/cjx064

DO - 10.1093/ejo/cjx064

M3 - Article

AN - SCOPUS:85051001232

SN - 0141-5387

VL - 40

SP - 343

EP - 349

JO - European Journal of Orthodontics

JF - European Journal of Orthodontics

IS - 4

ER -