The Effect of Topical Fluorides on Enamel Volume Loss from Erosion and Erosion-Abrasion in vitro

TY - JOUR

T1 - The Effect of Topical Fluorides on Enamel Volume Loss from Erosion and Erosion-Abrasion in vitro

AU - Austin, Rupert

PY - 2011/5/12

Y1 - 2011/5/12

N2 - Reduced erosive enamel wear has been demonstrated in vitro and in situ following topical applications of fluorides. Little is known about the protective effect during intermittent erosion and abrasion. The aim was to investigate the protective effect of highly concentrated fluoride solutions and a varnish on enamel in a cyclic erosion and erosion-abrasion model. 60 polished human enamel specimens (12 per group) were covered with polyvinyl tape to create a central 1/3 area for treatment with NaF (pH 8.0), SnF 2 (pH 2.6) or TiF 4 (pH 1.2) 0.5 M F solutions for 2 min, Bifluorid10 varnish (5% NaF + 5% CaF 2 , pH 5.5) for 20 s or deionised water (negative control). 2/3 remained as bilateral reference areas. 30 specimens (6 ! 5) were allocated to an erosion protocol (one cycle was 2 min in 0.01 M HCl and 60 min remineralisation in artificial saliva and 30 specimens (6 ! 5) to an erosion-abrasion protocol (similar to the erosion cycle, followed by tooth brushing with fluoride free toothpaste slurry (200 g, 120 linear strokes) for 2 min). The tape was removed and a 5 ! 3 mm central area was scanned by a white light con-focal profilometer with a 7 m spot size after the 3rd, 6th and 9th cycles. The distance between individual data points was 10 m. 3D data was analysed with volume loss as outcome. The tape was replaced between the respective cycles. The TiF 4 solution and Bifluorid10 varnish reduced volume loss significantly during the cyclic erosion protocol (90 and 38% respectively, p ! 0.05) whereas NaF and SnF 2 solutions did not. After 9 cycles of erosion-abrasion, the NaF and Bifluorid10 were the only groups that showed significantly less volume loss (38 and 50% respectively, p ! 0.05) compared to the control. In conclusion, the potential for highly concentrated fluoride preparations to provide long-term protection against erosion-abrasion remains uncertain

AB - Reduced erosive enamel wear has been demonstrated in vitro and in situ following topical applications of fluorides. Little is known about the protective effect during intermittent erosion and abrasion. The aim was to investigate the protective effect of highly concentrated fluoride solutions and a varnish on enamel in a cyclic erosion and erosion-abrasion model. 60 polished human enamel specimens (12 per group) were covered with polyvinyl tape to create a central 1/3 area for treatment with NaF (pH 8.0), SnF 2 (pH 2.6) or TiF 4 (pH 1.2) 0.5 M F solutions for 2 min, Bifluorid10 varnish (5% NaF + 5% CaF 2 , pH 5.5) for 20 s or deionised water (negative control). 2/3 remained as bilateral reference areas. 30 specimens (6 ! 5) were allocated to an erosion protocol (one cycle was 2 min in 0.01 M HCl and 60 min remineralisation in artificial saliva and 30 specimens (6 ! 5) to an erosion-abrasion protocol (similar to the erosion cycle, followed by tooth brushing with fluoride free toothpaste slurry (200 g, 120 linear strokes) for 2 min). The tape was removed and a 5 ! 3 mm central area was scanned by a white light con-focal profilometer with a 7 m spot size after the 3rd, 6th and 9th cycles. The distance between individual data points was 10 m. 3D data was analysed with volume loss as outcome. The tape was replaced between the respective cycles. The TiF 4 solution and Bifluorid10 varnish reduced volume loss significantly during the cyclic erosion protocol (90 and 38% respectively, p ! 0.05) whereas NaF and SnF 2 solutions did not. After 9 cycles of erosion-abrasion, the NaF and Bifluorid10 were the only groups that showed significantly less volume loss (38 and 50% respectively, p ! 0.05) compared to the control. In conclusion, the potential for highly concentrated fluoride preparations to provide long-term protection against erosion-abrasion remains uncertain

U2 - 10.1159/000328514

DO - 10.1159/000328514

M3 - Meeting abstract

SN - 0008-6568

VL - 45

SP - 174

EP - 242

JO - Caries research

JF - Caries research

IS - 2

M1 - 90

ER -