The ESCRT machinery: new functions in viral and cellular biology: new functions in viral and cellular biology

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Abstract

The ESCRT (endosomal sorting complex required for transport) machinery consists of a number of cytosolic proteins that make up three functional subcomplexes: ESCRT-I, ESCRT-II and ESCRT-III. These proteins function in multivesicular body formation and cell division and are co-opted by enveloped retroviruses to facilitate viral egress. Analysis of these functions may help illuminate conserved mechanisms of ESCRT function.
Original languageEnglish
Pages (from-to)195 - 199
Number of pages5
JournalBiochemical Society Transactions
Volume37
Issue numberPt 1
DOIs
Publication statusPublished - 2009
EventConference on ESCRTs - From Cell Biology to Pathogensis - Cambridge, ENGLAND
Duration: 26 Aug 200828 Aug 2008

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