Abstract
The ESCRT (endosomal sorting complex required for transport) machinery consists of a number of cytosolic proteins that make up three functional subcomplexes: ESCRT-I, ESCRT-II and ESCRT-III. These proteins function in multivesicular body formation and cell division and are co-opted by enveloped retroviruses to facilitate viral egress. Analysis of these functions may help illuminate conserved mechanisms of ESCRT function.
Original language | English |
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Pages (from-to) | 195 - 199 |
Number of pages | 5 |
Journal | Biochemical Society Transactions |
Volume | 37 |
Issue number | Pt 1 |
DOIs | |
Publication status | Published - 2009 |
Event | Conference on ESCRTs - From Cell Biology to Pathogensis - Cambridge, ENGLAND Duration: 26 Aug 2008 → 28 Aug 2008 |