TY - JOUR
T1 - The global role of biotechnology for non communicable disorders
AU - Zacchigna, Serena
AU - Giacca, Mauro
PY - 2018/10/10
Y1 - 2018/10/10
N2 - The World Health Organization (WHO) has tagged non-communicable diseases (NCDs) as one of the twenty-first century's major development challenges. NCDs account for over 15 million deaths annually and over 80% of those deaths occur in developing countries and among the poorest populations. Biotechnology presents unique opportunities to improve the early diagnosis and the treatment of NCDs. This review describes the major applications of biotechnology for a better clinical management of NCDs, i.e. the implementation of innovative diagnostic approaches and the production of innovative treatments, including those based on monoclonal antibodies, recombinant proteins, regulatory nucleic acids and cell-based therapies for regenerative medicine. In this context, it also examines the major challenges faced by biotechnology in developing countries.
AB - The World Health Organization (WHO) has tagged non-communicable diseases (NCDs) as one of the twenty-first century's major development challenges. NCDs account for over 15 million deaths annually and over 80% of those deaths occur in developing countries and among the poorest populations. Biotechnology presents unique opportunities to improve the early diagnosis and the treatment of NCDs. This review describes the major applications of biotechnology for a better clinical management of NCDs, i.e. the implementation of innovative diagnostic approaches and the production of innovative treatments, including those based on monoclonal antibodies, recombinant proteins, regulatory nucleic acids and cell-based therapies for regenerative medicine. In this context, it also examines the major challenges faced by biotechnology in developing countries.
KW - Cell therapy
KW - Diagnostics
KW - Monoclonal antibodies
KW - Non communicable disorders
KW - Recombinant proteins
KW - Small nuclei acids
UR - http://www.scopus.com/inward/record.url?scp=85051043429&partnerID=8YFLogxK
U2 - 10.1016/j.jbiotec.2018.07.043
DO - 10.1016/j.jbiotec.2018.07.043
M3 - Article
C2 - 30077584
AN - SCOPUS:85051043429
SN - 0168-1656
VL - 283
SP - 115
EP - 119
JO - JOURNAL OF BIOTECHNOLOGY
JF - JOURNAL OF BIOTECHNOLOGY
ER -