The MVQOLI successfully captured quality of life in African palliative care: a factor analysis

Lucy Selman, Richard J. Siegert, Irene J. Higginson, Godfrey Agupio, Natalya Dinat, Julia Downing, Liz Gwyther, Thandi Mashao, Keletso Mmoledi, Tony Moll, Lydia Mpanga Sebuyira, Barbara Ikin, Richard Harding

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


Objective: To examine the factor structure of the Missoula Vitas Quality of Life Index (MVQOLI) in palliative care patients in South Africa and Uganda and to assess the tool's appropriateness for measuring quality of life (QOL) in this context. Study Design and Setting: Cross-sectional survey using the MVQOLI, a 26-item QOL measure containing five subscales (Function, Symptoms, Interpersonal, Well being, and Transcendent), in five palliative care services in South Africa and Uganda. Results: Two hundred eighty-five patients were recruited; mean age was 40.1 years; 197 (69.1%) were female; primary diagnoses were human immunodeficiency virus infection (80.7%) and cancer (17.9%). A five-factor solution, accounting for 55% of variance, presented the best model of fit. The factors corresponded relatively closely to the original subscales, with only 4 of the 20 items not loading on the factor corresponding to the appropriate subscale. Internal consistency was high (alpha = 0.83). Conclusion: We found evidence of five factors underpinning the MVQOLI in a large sample of South African and Ugandan palliative care patients. The five factors corresponded reasonably well to the original subscales, suggesting that it is a promising measure for use in this population. However, further testing of its psychometric properties, comprehensibility, and scoring require further research in sub-Saharan Africa. (C) 2011 Elsevier Inc. All rights reserved.
Original languageEnglish
Pages (from-to)913 - 924
Number of pages12
JournalJournal of Clinical Epidemiology
Issue number8
Publication statusPublished - Aug 2011


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