Abstract
Image registration involves orienting and scaling multiple images acquired at different times or in different modalities so that they are accurately aligned. Composite registered images may usefully display complementary information; they may for example be used to give anatomical context to functional information from SPECT by incorporating it within physical structures seen in CT, or used to highlight the difference between pre- and post-treatment by using images from the same modality. We have used image registration techniques in conjunction with the Centre of Medical Image Research (CoMIR) at Leeds to quantify the tumour mass and tumour uptake and retention of I-131 meta iodobenzylguanidine (mIBG) in a 34-year-old man undergoing I-131-mIBG therapy for inoperable intraabdominal metastatic paraganglioma. Pre-treatment I-123-mIBG SPECT and CT images were registered in order to assist in treatment planning. I-131-mIBG SPECT images acquired during treatment were used for verification and post-treatment I-123-mIBG SPECT and CT images were registered with the original images in order to quantify tumour response. The relative success of the techniques and the implications for future treatments are discussed.
Original language | English |
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Title of host publication | QUANTITATIVE IMAGING IN ONCOLOGY |
Editors | K Faulkner, B Carey, A Crellin, RM Harrison |
Place of Publication | LONDON |
Publisher | BRITISH INST RADIOLOGY |
Pages | 133-136 |
Number of pages | 4 |
ISBN (Print) | 0905749375 |
Publication status | Published - 1996 |
Event | 19th L H Gray Conference on Quantitative Imaging in Oncology - NEWCASTLE TYNE Duration: 3 Apr 1995 → 7 Apr 1995 |
Conference
Conference | 19th L H Gray Conference on Quantitative Imaging in Oncology |
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City | NEWCASTLE TYNE |
Period | 3/04/1995 → 7/04/1995 |