The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and Recommended Evaluation and Management: A Systematic Review, Meta-Analysis, GRADE Assessment, and International Consensus Approach

Matthew Greenhawt; Elissa M. Abrams; Marcus Shaker; Derek K. Chu; David Khan; Cem Akin; Waleed Alqurashi; Peter Arkwright; James L. Baldwin; Moshe Ben-Shoshan; Jonathan Bernstein; Theresa Bingemann; Katharina Blumchen; Aideen Byrne; Antonio Bognanni; Dianne Campbell; Ronna Campbell; Zain Chagla; Edmond S. Chan; Jeffrey Chan; Pasquale Comberiati; Timothy E. Dribin; Anne K. Ellis; David M. Fleischer; Adam Fox; Pamela A. Frischmeyer-Guerrerio; Remi Gagnon; Mitchell H. Grayson; Caroline C. Horner; Jonathan Hourihane; Constance H. Katelaris; Harold Kim; John M. Kelso; David Lang; Dennis Ledford; Michael Levin; Jay Lieberman; Richard Loh; Doug Mack; Bruce MaZer; Giselle Mosnaim; Daniel Munblit; S. ShahZad Mustafa; Anil Nanda; John Oppenheimer; Kirsten P. Perrett; Allison Ramsey; Matthew Rank; Kara Robertson; Javed Sheikh; Jonathan M. Spergel; David Stukus; Mimi L. K. Tang; James M. Tracy; Paul J. Turner; Anna Whalen-Browne; Dana Wallace; Julie Wang; Susan Waserman; John K. Witry; Margitta Worm; Timothy K. Vander Leek; David B. K. Golden

doi:10.1016/j.jaip.2021.06.006

The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and Recommended Evaluation and Management: A Systematic Review, Meta-Analysis, GRADE Assessment, and International Consensus Approach

Matthew Greenhawt, Elissa M. Abrams, Marcus Shaker, Derek K. Chu, David Khan, Cem Akin, Waleed Alqurashi, Peter Arkwright, James L. Baldwin, Moshe Ben-Shoshan, Jonathan Bernstein, Theresa Bingemann, Katharina Blumchen, Aideen Byrne, Antonio Bognanni, Dianne Campbell, Ronna Campbell, Zain Chagla, Edmond S. Chan, Jeffrey ChanPasquale Comberiati, Timothy E. Dribin, Anne K. Ellis, David M. Fleischer, Adam Fox, Pamela A. Frischmeyer-Guerrerio, Remi Gagnon, Mitchell H. Grayson, Caroline C. Horner, Jonathan Hourihane, Constance H. Katelaris, Harold Kim, John M. Kelso, David Lang, Dennis Ledford, Michael Levin, Jay Lieberman, Richard Loh, Doug Mack, Bruce MaZer, Giselle Mosnaim, Daniel Munblit, S. ShahZad Mustafa, Anil Nanda, John Oppenheimer, Kirsten P. Perrett, Allison Ramsey, Matthew Rank, Kara Robertson, Javed Sheikh, Jonathan M. Spergel, David Stukus, Mimi L. K. Tang, James M. Tracy, Paul J. Turner, Anna Whalen-Browne, Dana Wallace, Julie Wang, Susan Waserman, John K. Witry, Margitta Worm, Timothy K. Vander Leek, David B. K. Golden

Research output: Contribution to journal › Review article › peer-review

174 Citations (Scopus)

Original language	English
Pages (from-to)	3546-3567
Journal	The Journal of Allergy and Clinical Immunology: In Practice
Volume	9
Issue number	10
DOIs	https://doi.org/10.1016/j.jaip.2021.06.006
Publication status	Published - Oct 2021

Keywords

SARS-CoV-2
COVID-19
Vaccination
Adenovirus-vector vaccine
mRNA vaccine
Anaphylaxis
Allergic reactions
Polyethylene glycol
Polysorbate 80
Skin testing
Shared decision making
GRADE
Allergy
Allergy specialist

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.jaip.2021.06.006

Cite this

Greenhawt, M., Abrams, E. M., Shaker, M., Chu, D. K., Khan, D., Akin, C., Alqurashi, W., Arkwright, P., Baldwin, J. L., Ben-Shoshan, M., Bernstein, J., Bingemann, T., Blumchen, K., Byrne, A., Bognanni, A., Campbell, D., Campbell, R., Chagla, Z., Chan, E. S., ... Golden, D. B. K. (2021). The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and Recommended Evaluation and Management: A Systematic Review, Meta-Analysis, GRADE Assessment, and International Consensus Approach. The Journal of Allergy and Clinical Immunology: In Practice, 9(10), 3546-3567. https://doi.org/10.1016/j.jaip.2021.06.006

@article{f0dcfae48fc8433daa4b4d0df5c56fc5,

title = "The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and Recommended Evaluation and Management: A Systematic Review, Meta-Analysis, GRADE Assessment, and International Consensus Approach",

keywords = "SARS-CoV-2, COVID-19, Vaccination, Adenovirus-vector vaccine, mRNA vaccine, Anaphylaxis, Allergic reactions, Polyethylene glycol, Polysorbate 80, Skin testing, Shared decision making, GRADE, Allergy, Allergy specialist",

author = "Matthew Greenhawt and Abrams, {Elissa M.} and Marcus Shaker and Chu, {Derek K.} and David Khan and Cem Akin and Waleed Alqurashi and Peter Arkwright and Baldwin, {James L.} and Moshe Ben-Shoshan and Jonathan Bernstein and Theresa Bingemann and Katharina Blumchen and Aideen Byrne and Antonio Bognanni and Dianne Campbell and Ronna Campbell and Zain Chagla and Chan, {Edmond S.} and Jeffrey Chan and Pasquale Comberiati and Dribin, {Timothy E.} and Ellis, {Anne K.} and Fleischer, {David M.} and Adam Fox and Frischmeyer-Guerrerio, {Pamela A.} and Remi Gagnon and Grayson, {Mitchell H.} and Horner, {Caroline C.} and Jonathan Hourihane and Katelaris, {Constance H.} and Harold Kim and Kelso, {John M.} and David Lang and Dennis Ledford and Michael Levin and Jay Lieberman and Richard Loh and Doug Mack and Bruce MaZer and Giselle Mosnaim and Daniel Munblit and Mustafa, {S. ShahZad} and Anil Nanda and John Oppenheimer and Perrett, {Kirsten P.} and Allison Ramsey and Matthew Rank and Kara Robertson and Javed Sheikh and Spergel, {Jonathan M.} and David Stukus and Tang, {Mimi L. K.} and Tracy, {James M.} and Turner, {Paul J.} and Anna Whalen-Browne and Dana Wallace and Julie Wang and Susan Waserman and Witry, {John K.} and Margitta Worm and {Vander Leek}, {Timothy K.} and Golden, {David B. K.}",

year = "2021",

month = oct,

doi = "10.1016/j.jaip.2021.06.006",

language = "English",

volume = "9",

pages = "3546--3567",

journal = "The Journal of Allergy and Clinical Immunology: In Practice",

issn = "2213-2198",

publisher = "Elsevier",

number = "10",

}

Greenhawt, M, Abrams, EM, Shaker, M, Chu, DK, Khan, D, Akin, C, Alqurashi, W, Arkwright, P, Baldwin, JL, Ben-Shoshan, M, Bernstein, J, Bingemann, T, Blumchen, K, Byrne, A, Bognanni, A, Campbell, D, Campbell, R, Chagla, Z, Chan, ES, Chan, J, Comberiati, P, Dribin, TE, Ellis, AK, Fleischer, DM, Fox, A, Frischmeyer-Guerrerio, PA, Gagnon, R, Grayson, MH, Horner, CC, Hourihane, J, Katelaris, CH, Kim, H, Kelso, JM, Lang, D, Ledford, D, Levin, M, Lieberman, J, Loh, R, Mack, D, MaZer, B, Mosnaim, G, Munblit, D, Mustafa, SS, Nanda, A, Oppenheimer, J, Perrett, KP, Ramsey, A, Rank, M, Robertson, K, Sheikh, J, Spergel, JM, Stukus, D, Tang, MLK, Tracy, JM, Turner, PJ, Whalen-Browne, A, Wallace, D, Wang, J, Waserman, S, Witry, JK, Worm, M, Vander Leek, TK & Golden, DBK 2021, 'The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and Recommended Evaluation and Management: A Systematic Review, Meta-Analysis, GRADE Assessment, and International Consensus Approach', The Journal of Allergy and Clinical Immunology: In Practice, vol. 9, no. 10, pp. 3546-3567. https://doi.org/10.1016/j.jaip.2021.06.006

The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and Recommended Evaluation and Management: A Systematic Review, Meta-Analysis, GRADE Assessment, and International Consensus Approach. / Greenhawt, Matthew; Abrams, Elissa M.; Shaker, Marcus et al.
In: The Journal of Allergy and Clinical Immunology: In Practice, Vol. 9, No. 10, 10.2021, p. 3546-3567.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and Recommended Evaluation and Management: A Systematic Review, Meta-Analysis, GRADE Assessment, and International Consensus Approach

AU - Greenhawt, Matthew

AU - Abrams, Elissa M.

AU - Shaker, Marcus

AU - Chu, Derek K.

AU - Khan, David

AU - Akin, Cem

AU - Alqurashi, Waleed

AU - Arkwright, Peter

AU - Baldwin, James L.

AU - Ben-Shoshan, Moshe

AU - Bernstein, Jonathan

AU - Bingemann, Theresa

AU - Blumchen, Katharina

AU - Byrne, Aideen

AU - Bognanni, Antonio

AU - Campbell, Dianne

AU - Campbell, Ronna

AU - Chagla, Zain

AU - Chan, Edmond S.

AU - Chan, Jeffrey

AU - Comberiati, Pasquale

AU - Dribin, Timothy E.

AU - Ellis, Anne K.

AU - Fleischer, David M.

AU - Fox, Adam

AU - Frischmeyer-Guerrerio, Pamela A.

AU - Gagnon, Remi

AU - Grayson, Mitchell H.

AU - Horner, Caroline C.

AU - Hourihane, Jonathan

AU - Katelaris, Constance H.

AU - Kim, Harold

AU - Kelso, John M.

AU - Lang, David

AU - Ledford, Dennis

AU - Levin, Michael

AU - Lieberman, Jay

AU - Loh, Richard

AU - Mack, Doug

AU - MaZer, Bruce

AU - Mosnaim, Giselle

AU - Munblit, Daniel

AU - Mustafa, S. ShahZad

AU - Nanda, Anil

AU - Oppenheimer, John

AU - Perrett, Kirsten P.

AU - Ramsey, Allison

AU - Rank, Matthew

AU - Robertson, Kara

AU - Sheikh, Javed

AU - Spergel, Jonathan M.

AU - Stukus, David

AU - Tang, Mimi L. K.

AU - Tracy, James M.

AU - Turner, Paul J.

AU - Whalen-Browne, Anna

AU - Wallace, Dana

AU - Wang, Julie

AU - Waserman, Susan

AU - Witry, John K.

AU - Worm, Margitta

AU - Vander Leek, Timothy K.

AU - Golden, David B. K.

PY - 2021/10

Y1 - 2021/10

KW - SARS-CoV-2

KW - COVID-19

KW - Vaccination

KW - Adenovirus-vector vaccine

KW - mRNA vaccine

KW - Anaphylaxis

KW - Allergic reactions

KW - Polyethylene glycol

KW - Polysorbate 80

KW - Skin testing

KW - Shared decision making

KW - GRADE

KW - Allergy

KW - Allergy specialist

U2 - 10.1016/j.jaip.2021.06.006

DO - 10.1016/j.jaip.2021.06.006

M3 - Review article

SN - 2213-2198

VL - 9

SP - 3546

EP - 3567

JO - The Journal of Allergy and Clinical Immunology: In Practice

JF - The Journal of Allergy and Clinical Immunology: In Practice

IS - 10

ER -

Greenhawt M, Abrams EM, Shaker M, Chu DK, Khan D, Akin C et al. The Risk of Allergic Reaction to SARS-CoV-2 Vaccines and Recommended Evaluation and Management: A Systematic Review, Meta-Analysis, GRADE Assessment, and International Consensus Approach. The Journal of Allergy and Clinical Immunology: In Practice. 2021 Oct;9(10):3546-3567. doi: 10.1016/j.jaip.2021.06.006