The role of cardiovascular magnetic resonance in the evaluation of acute myocarditis and inflammatory cardiomyopathies in clinical practice - a comprehensive review

TY - JOUR

T1 - The role of cardiovascular magnetic resonance in the evaluation of acute myocarditis and inflammatory cardiomyopathies in clinical practice - a comprehensive review

AU - Ismail, Tevfik F.

AU - Hua, Alina

AU - Plein, Sven

AU - D'cruz, David P.

AU - Fernando, Michelle M.A.

AU - Friedrich, Matthias G.

AU - Zellweger, Michael J.

AU - Giorgetti, Assuero

AU - Caobelli, Federico

AU - Haaf, Philip

N1 - Publisher Copyright: © 2022 Published on behalf of the European Society of Cardiology. All rights reserved.

PY - 2022/4/1

Y1 - 2022/4/1

N2 - Inflammatory cardiomyopathy (I-CMP) is defined as myocarditis in association with cardiac dysfunction and/or ventricular remodelling. It is characterized by inflammatory cell infiltration into the myocardium and has heterogeneous infectious and non-infectious aetiologies. A complex interplay of genetic, autoimmune, and environmental factors contributes to the substantial risk of deteriorating cardiac function, acute heart failure, and arrhythmia as well as chronic dilated cardiomyopathy and its sequelae. Multi-parametric cardiovascular magnetic resonance (CMR) imaging is sensitive to many tissue changes that occur during myocardial inflammation, regardless of its aetiology. In this review, we summarize the various aetiologies of I-CMP and illustrate how CMR contributes to non-invasive diagnosis.

AB - Inflammatory cardiomyopathy (I-CMP) is defined as myocarditis in association with cardiac dysfunction and/or ventricular remodelling. It is characterized by inflammatory cell infiltration into the myocardium and has heterogeneous infectious and non-infectious aetiologies. A complex interplay of genetic, autoimmune, and environmental factors contributes to the substantial risk of deteriorating cardiac function, acute heart failure, and arrhythmia as well as chronic dilated cardiomyopathy and its sequelae. Multi-parametric cardiovascular magnetic resonance (CMR) imaging is sensitive to many tissue changes that occur during myocardial inflammation, regardless of its aetiology. In this review, we summarize the various aetiologies of I-CMP and illustrate how CMR contributes to non-invasive diagnosis.

UR - https://www.scopus.com/pages/publications/85128000484

U2 - 10.1093/ehjci/jeac021

DO - 10.1093/ehjci/jeac021

M3 - Review article

C2 - 35167664

AN - SCOPUS:85128000484

SN - 2047-2404

VL - 23

SP - 450

EP - 464

JO - European Heart Journal Cardiovascular Imaging

JF - European Heart Journal Cardiovascular Imaging

IS - 4

ER -