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The role of muscle mechano and metaboreflexes in the control of ventilation: breathless with (over) excitement?

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The role of muscle mechano and metaboreflexes in the control of ventilation : breathless with (over) excitement? / White, Michael; Bruce, Richard.

In: Experimental Physiology, Vol. 105, No. 12, 01.12.2020, p. 2250-2253.

Research output: Contribution to journalArticle

Harvard

White, M & Bruce, R 2020, 'The role of muscle mechano and metaboreflexes in the control of ventilation: breathless with (over) excitement?', Experimental Physiology, vol. 105, no. 12, pp. 2250-2253. https://doi.org/10.1113/EP088460

APA

White, M., & Bruce, R. (2020). The role of muscle mechano and metaboreflexes in the control of ventilation: breathless with (over) excitement? Experimental Physiology, 105(12), 2250-2253. https://doi.org/10.1113/EP088460

Vancouver

White M, Bruce R. The role of muscle mechano and metaboreflexes in the control of ventilation: breathless with (over) excitement? Experimental Physiology. 2020 Dec 1;105(12):2250-2253. https://doi.org/10.1113/EP088460

Author

White, Michael ; Bruce, Richard. / The role of muscle mechano and metaboreflexes in the control of ventilation : breathless with (over) excitement?. In: Experimental Physiology. 2020 ; Vol. 105, No. 12. pp. 2250-2253.

Bibtex Download

@article{3f941be4277e41dbb9359e404cef279c,
title = "The role of muscle mechano and metaboreflexes in the control of ventilation: breathless with (over) excitement?",
abstract = "Mechanically and metabolically sensitive thin fibre (group III and IV) muscle afferents are activated during exercise, causing reflex cardiovascular responses that are essential to normal cardiovascular control. Impaired exercise performance in some disease states can be linked to abnormal muscle mechanoreflex and muscle metaboreflex activity. A role for this same afferent feedback in contributing to the hyperpnoea of exercise and the dyspnoea experienced by some patient groups on exercise has recently received increased attention. Evidence is summarised here that supports a role for muscle mechanoreflex and muscle metaboreflex involvement in the human ventilatory response to exercise and also their synergistic interaction with the central chemoreflex during muscular activity. The effects of local muscle training induced attenuation of the human muscle metaboreflex on this synergistic interaction and associated decrease in ventilation is discussed.",
keywords = "exercise physiology, respiratory control, thin fibre muscle afferent",
author = "Michael White and Richard Bruce",
year = "2020",
month = dec,
day = "1",
doi = "10.1113/EP088460",
language = "English",
volume = "105",
pages = "2250--2253",
journal = "Experimental Physiology",
issn = "0958-0670",
publisher = "Wiley-Blackwell",
number = "12",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - The role of muscle mechano and metaboreflexes in the control of ventilation

T2 - breathless with (over) excitement?

AU - White, Michael

AU - Bruce, Richard

PY - 2020/12/1

Y1 - 2020/12/1

N2 - Mechanically and metabolically sensitive thin fibre (group III and IV) muscle afferents are activated during exercise, causing reflex cardiovascular responses that are essential to normal cardiovascular control. Impaired exercise performance in some disease states can be linked to abnormal muscle mechanoreflex and muscle metaboreflex activity. A role for this same afferent feedback in contributing to the hyperpnoea of exercise and the dyspnoea experienced by some patient groups on exercise has recently received increased attention. Evidence is summarised here that supports a role for muscle mechanoreflex and muscle metaboreflex involvement in the human ventilatory response to exercise and also their synergistic interaction with the central chemoreflex during muscular activity. The effects of local muscle training induced attenuation of the human muscle metaboreflex on this synergistic interaction and associated decrease in ventilation is discussed.

AB - Mechanically and metabolically sensitive thin fibre (group III and IV) muscle afferents are activated during exercise, causing reflex cardiovascular responses that are essential to normal cardiovascular control. Impaired exercise performance in some disease states can be linked to abnormal muscle mechanoreflex and muscle metaboreflex activity. A role for this same afferent feedback in contributing to the hyperpnoea of exercise and the dyspnoea experienced by some patient groups on exercise has recently received increased attention. Evidence is summarised here that supports a role for muscle mechanoreflex and muscle metaboreflex involvement in the human ventilatory response to exercise and also their synergistic interaction with the central chemoreflex during muscular activity. The effects of local muscle training induced attenuation of the human muscle metaboreflex on this synergistic interaction and associated decrease in ventilation is discussed.

KW - exercise physiology

KW - respiratory control

KW - thin fibre muscle afferent

UR - http://www.scopus.com/inward/record.url?scp=85091434148&partnerID=8YFLogxK

U2 - 10.1113/EP088460

DO - 10.1113/EP088460

M3 - Article

AN - SCOPUS:85091434148

VL - 105

SP - 2250

EP - 2253

JO - Experimental Physiology

JF - Experimental Physiology

SN - 0958-0670

IS - 12

ER -

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