The role of uterine artery Doppler in predicting adverse pregnancy outcome

A T Papageorghiou; C K H Yu; K H Nicolaides

The role of uterine artery Doppler in predicting adverse pregnancy outcome

A T Papageorghiou, C K H Yu, K H Nicolaides

Research output: Contribution to journal › Conference paper

196 Citations (Scopus)

Abstract

The complications of placental insufficiency, pre-eclampsia and fetal growth restriction (FGR) are major causes of perinatal as well as maternal morbidity and mortality. In normal pregnancy, impedance to flow in the uterine arteries decreases with gestation, and histopathological studies suggest that this is due to trophoblastic invasion of the spiral arteries and their conversion into low-resistance vessels. Failure of trophoblastic invasion is associated with complications of uteroplacental insufficiency. Several Doppler screening studies, both in the second and more recently in the first trimester of pregnancy, have demonstrated an association between increased impedance to flow in the uterine arteries and subsequent development of pre-eclampsia, FGR and perinatal death.

Original language	English
Pages (from-to)	383 - 396
Number of pages	14
Journal	Best Practice & Research Clinical Obstetrics & Gynaecology
Volume	18
Issue number	3
Publication status	Published - Jun 2004
Event	7th International Symposium on Intrauterine Surveillance - London, ENGLAND Duration: 1 Jan 2004 → …

Cite this

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title = "The role of uterine artery Doppler in predicting adverse pregnancy outcome",

abstract = "The complications of placental insufficiency, pre-eclampsia and fetal growth restriction (FGR) are major causes of perinatal as well as maternal morbidity and mortality. In normal pregnancy, impedance to flow in the uterine arteries decreases with gestation, and histopathological studies suggest that this is due to trophoblastic invasion of the spiral arteries and their conversion into low-resistance vessels. Failure of trophoblastic invasion is associated with complications of uteroplacental insufficiency. Several Doppler screening studies, both in the second and more recently in the first trimester of pregnancy, have demonstrated an association between increased impedance to flow in the uterine arteries and subsequent development of pre-eclampsia, FGR and perinatal death.",

author = "Papageorghiou, {A T} and Yu, {C K H} and Nicolaides, {K H}",

year = "2004",

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journal = "Best Practice & Research Clinical Obstetrics & Gynaecology",

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T1 - The role of uterine artery Doppler in predicting adverse pregnancy outcome

AU - Papageorghiou, A T

AU - Yu, C K H

AU - Nicolaides, K H

PY - 2004/6

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N2 - The complications of placental insufficiency, pre-eclampsia and fetal growth restriction (FGR) are major causes of perinatal as well as maternal morbidity and mortality. In normal pregnancy, impedance to flow in the uterine arteries decreases with gestation, and histopathological studies suggest that this is due to trophoblastic invasion of the spiral arteries and their conversion into low-resistance vessels. Failure of trophoblastic invasion is associated with complications of uteroplacental insufficiency. Several Doppler screening studies, both in the second and more recently in the first trimester of pregnancy, have demonstrated an association between increased impedance to flow in the uterine arteries and subsequent development of pre-eclampsia, FGR and perinatal death.

AB - The complications of placental insufficiency, pre-eclampsia and fetal growth restriction (FGR) are major causes of perinatal as well as maternal morbidity and mortality. In normal pregnancy, impedance to flow in the uterine arteries decreases with gestation, and histopathological studies suggest that this is due to trophoblastic invasion of the spiral arteries and their conversion into low-resistance vessels. Failure of trophoblastic invasion is associated with complications of uteroplacental insufficiency. Several Doppler screening studies, both in the second and more recently in the first trimester of pregnancy, have demonstrated an association between increased impedance to flow in the uterine arteries and subsequent development of pre-eclampsia, FGR and perinatal death.

UR - http://www.scopus.com/inward/record.url?scp=3242713417&partnerID=8YFLogxK

M3 - Conference paper

VL - 18

SP - 383

EP - 396

JO - Best Practice & Research Clinical Obstetrics & Gynaecology

JF - Best Practice & Research Clinical Obstetrics & Gynaecology

IS - 3

T2 - 7th International Symposium on Intrauterine Surveillance

Y2 - 1 January 2004

ER -

The role of uterine artery Doppler in predicting adverse pregnancy outcome

Abstract

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