The sentinel node negative axilla: Is it a no-go zone?

TY - JOUR

T1 - The sentinel node negative axilla: Is it a no-go zone?

AU - Fentiman, I S

AU - Mansel, R E

PY - 2002

Y1 - 2002

N2 - The technique of sentinel node biopsy (SNB) presents a great opportunity to reduce the morbidity of surgical treatment of breast cancer. Using either dye, isotope or a combination, after completing a learning process a sensitivity of 80-99% may be achieved, Most surgeons would aim for a sensitivity of 95% but this will mean that 5% of patients will be under-staged, with disease within the axilla and possibly inappropriate advice with regard to adjuvant systemic therapy. Injudicious use of sentinel biopsy will lead to more local relapses and may diminish or neutralize gains from systemic therapy. (C) 2002, Elsevier Science Ltd. All rights reserved.

AB - The technique of sentinel node biopsy (SNB) presents a great opportunity to reduce the morbidity of surgical treatment of breast cancer. Using either dye, isotope or a combination, after completing a learning process a sensitivity of 80-99% may be achieved, Most surgeons would aim for a sensitivity of 95% but this will mean that 5% of patients will be under-staged, with disease within the axilla and possibly inappropriate advice with regard to adjuvant systemic therapy. Injudicious use of sentinel biopsy will lead to more local relapses and may diminish or neutralize gains from systemic therapy. (C) 2002, Elsevier Science Ltd. All rights reserved.

U2 - 10.1054/ctrv.2002.0251

DO - 10.1054/ctrv.2002.0251

M3 - Literature review

VL - 28

SP - 1

EP - 3

JO - Cancer Treatment Reviews

JF - Cancer Treatment Reviews

IS - 1

ER -