The time of day that etidronate is ingested does not influence its therapeutic effect in osteoporosis

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Abstract

To investigate whether the therapeutic effect of etidronate is affected by the time of ingestion we have retrospectively studied 110 osteoporotic patients. They had been taking etidronate according to the manufacturer's instructions for a mean duration of 2.6 years either on waking (n = 47), on retiring (n = 47), or during the day (n = 16). No significant differences were found between the three groups with respect to percentage change in bone mineral density at all sites either for the first year of treatment or for the mean yearly percent change throughout the total course of treatment. These findings suggest that the time of ingestion of etidronate does not influence the therapeutic effect if a two how fast before and after ingestion is adhered to.
Original languageEnglish
Pages (from-to)62-64
Number of pages3
JournalScandinavian Journal of Rheumatology
Volume29
Issue number1
Publication statusPublished - 2000

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