The Ultra High Risk Approach to Define Psychosis Risk

Alison R. Yung; Paolo Fusar-Poli; Barnaby Nelson

doi:10.2174/138161212799316299

The Ultra High Risk Approach to Define Psychosis Risk

Alison R. Yung^*, Paolo Fusar-Poli, Barnaby Nelson

^*Corresponding author for this work

University of Melbourne

Research output: Contribution to journal › Literature review › peer-review

23 Citations (Scopus)

Abstract

Although prodromal symptoms of psychosis have long been recognized, the clinical management of psychotic disorders conventionally begins at the first episode of frank psychosis, and, until recently, the period immediately preceding the first episode received relatively little attention. Over the last fifteen years, there has been increasing academic and clinical interest in people presenting with potentially prodromal symptoms. This clinical syndrome has been termed an "At Risk Mental State", and operationalised criteria, the "Ultra High Risk (UHR)", or "Clinical High Risk" criteria, have been developed to identify the syndrome. We will review here the mainstreams of the UHR paradigms focusing on the conceptual basis, potentials and limtations in current psychiatric research.

Original language	English
Article number	N/A
Pages (from-to)	346-350
Number of pages	5
Journal	Current Pharmaceutical Design
Volume	18
Issue number	4
DOIs	https://doi.org/10.2174/138161212799316299
Publication status	Published - Feb 2012

Keywords

Psychosis
schizophrenia
prodrome
RANDOMIZED CONTROLLED-TRIAL
YOUNG-PEOPLE
FOLLOW-UP
DSM-V
INTERRATER RELIABILITY
PRODROMAL PSYCHOSIS
PREDICTIVE-VALIDITY
COGNITIVE THERAPY
INITIAL PRODROME
CLINICAL-SAMPLE

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Cite this

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title = "The Ultra High Risk Approach to Define Psychosis Risk",

abstract = "Although prodromal symptoms of psychosis have long been recognized, the clinical management of psychotic disorders conventionally begins at the first episode of frank psychosis, and, until recently, the period immediately preceding the first episode received relatively little attention. Over the last fifteen years, there has been increasing academic and clinical interest in people presenting with potentially prodromal symptoms. This clinical syndrome has been termed an {"}At Risk Mental State{"}, and operationalised criteria, the {"}Ultra High Risk (UHR){"}, or {"}Clinical High Risk{"} criteria, have been developed to identify the syndrome. We will review here the mainstreams of the UHR paradigms focusing on the conceptual basis, potentials and limtations in current psychiatric research.",

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author = "Yung, {Alison R.} and Paolo Fusar-Poli and Barnaby Nelson",

year = "2012",

month = feb,

doi = "10.2174/138161212799316299",

language = "English",

volume = "18",

pages = "346--350",

journal = "Current Pharmaceutical Design",

issn = "1381-6128",

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TY - JOUR

T1 - The Ultra High Risk Approach to Define Psychosis Risk

AU - Yung, Alison R.

AU - Fusar-Poli, Paolo

AU - Nelson, Barnaby

PY - 2012/2

Y1 - 2012/2

N2 - Although prodromal symptoms of psychosis have long been recognized, the clinical management of psychotic disorders conventionally begins at the first episode of frank psychosis, and, until recently, the period immediately preceding the first episode received relatively little attention. Over the last fifteen years, there has been increasing academic and clinical interest in people presenting with potentially prodromal symptoms. This clinical syndrome has been termed an "At Risk Mental State", and operationalised criteria, the "Ultra High Risk (UHR)", or "Clinical High Risk" criteria, have been developed to identify the syndrome. We will review here the mainstreams of the UHR paradigms focusing on the conceptual basis, potentials and limtations in current psychiatric research.

AB - Although prodromal symptoms of psychosis have long been recognized, the clinical management of psychotic disorders conventionally begins at the first episode of frank psychosis, and, until recently, the period immediately preceding the first episode received relatively little attention. Over the last fifteen years, there has been increasing academic and clinical interest in people presenting with potentially prodromal symptoms. This clinical syndrome has been termed an "At Risk Mental State", and operationalised criteria, the "Ultra High Risk (UHR)", or "Clinical High Risk" criteria, have been developed to identify the syndrome. We will review here the mainstreams of the UHR paradigms focusing on the conceptual basis, potentials and limtations in current psychiatric research.

KW - Psychosis

KW - schizophrenia

KW - prodrome

KW - RANDOMIZED CONTROLLED-TRIAL

KW - YOUNG-PEOPLE

KW - FOLLOW-UP

KW - DSM-V

KW - INTERRATER RELIABILITY

KW - PRODROMAL PSYCHOSIS

KW - PREDICTIVE-VALIDITY

KW - COGNITIVE THERAPY

KW - INITIAL PRODROME

KW - CLINICAL-SAMPLE

U2 - 10.2174/138161212799316299

DO - 10.2174/138161212799316299

M3 - Literature review

SN - 1381-6128

VL - 18

SP - 346

EP - 350

JO - Current Pharmaceutical Design

JF - Current Pharmaceutical Design

IS - 4

M1 - N/A

ER -

The Ultra High Risk Approach to Define Psychosis Risk

Abstract

Keywords

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