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The value of combined cervical length measurement and fetal fibronectin testing to predict spontaneous preterm birth in asymptomatic high-risk women

Research output: Contribution to journalArticlepeer-review

Lauren A. Bolt, Manju Chandiramani, Annemarie De Greeff, Paul T. Seed, James Kurtzman, Andrew H. Shennan

Original languageEnglish
Pages (from-to)928 - 932
Number of pages5
Issue number7
PublishedJul 2011

King's Authors


Methods. aEuro integral One hundred and forty-seven asymptomatic women at high-risk of PTB were referred to specialist antenatal clinics and underwent CL and fFN testing over a 12-month period. Women had both tests undertaken between 22 aEuroS25 mm. With a known CL, the addition of positive fFN yielded significant hazard ratios regardless of CL (CL aEuroS > aEuroS25 mm-HR 2.78, CL aEuroS <a parts per thousand currency sign25 mm-HR 3.14, p aEuroS <0.05). The hazard ratios were insignificant when CL results were added to a known fFN. Conclusions. aEuro integral In high-risk asymptomatic women, fFN may be used as a primary screening tool with CL measurement being reserved for those with a positive fFN result. Further prospective studies are needed to confirm our findings.

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